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OAT

Organic anion transporters (OATs) are the secondary/tertiary active transporter proteins that regulate anion balance in the body. They are primarily expressed in the kidney and liver and control the excretion of common drugs, toxins, and endogenous metabolites into the urine.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13259 URAT1 inhibitor 1 2268720-62-1 98%
URAT1 inhibitor 1
URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.
T6875 Lesinurad 878672-00-5 99.83%
Lesinurad
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a...
T3994 Verinurad 1352792-74-5 99.22%
Verinurad
Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
T3783 Fraxin 524-30-1 99.19%
Fraxin
Fraxin (Fraxoside) is a glucoside of fraxetin.
T19866 Indican 487-60-5 98%
Indican
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
T20545 Benzarone 1477-19-6 98%
Benzarone
Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.
T77517 URAT1 inhibitor 7 1632002-28-8 98%
URAT1 inhibitor 7
URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of...
T15160 Dotinurad 1285572-51-1 98%
Dotinurad
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).
T61048 Puliginurad 2013582-27-7 98%
Puliginurad
Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can ...
URAT1 inhibitor 1
T13259
URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.
Lesinurad
T6875
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a...
Verinurad
T3994
Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
Fraxin
T3783
Fraxin (Fraxoside) is a glucoside of fraxetin.
Indican
T19866
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
Benzarone
T20545
Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.
URAT1 inhibitor 7
T77517
URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of...
Dotinurad
T15160
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).
Puliginurad
T61048
Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can ...
TargetMol