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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine is a catecholamine and a phenethylamine. Its structure differs from that of epinephrine only in that epinephrine has a methyl group attached to its nitrogen, whereas the methyl group is replaced by a hydrogen atom in norepinephrine. The prefix nor- is derived as an abbreviation of the word "normal", used to indicate a demethylated compound.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T33342L Methyl reserpate 2901-66-8 99.48%
Methyl reserpate
Methyl reserpate (NSC 81464), a yohimbine-type alkaloid derived from the roots and leaves of Rauwolfia vomitoria, inhibits the transport of norepinephrine into c...
T2579 Reboxetine 71620-89-8
Reboxetine
Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) sa...
T26622 Ampreloxetine 1227056-84-9 98%
Ampreloxetine
Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.
T20886 Atomoxetine 83015-26-3 98%
Atomoxetine
Atomoxetine (HSDB 7352) is a selective norepinephrine inhibitor that may cause an increase in blood pressure by increasing norepinephrine concentrations in perip...
T9540 Phenelzine 51-71-8 98%
Phenelzine
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
T1471 Duloxetine hydrochloride 136434-34-9 99.97%
Duloxetine hydrochloride
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE...
T0031 Ziprasidone hydrochloride monohydrate 138982-67-9 99.95%
Ziprasidone hydrochloride monohydrate
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic ac...
T1540 Doxepin hydrochloride 1229-29-4 99.91%
Doxepin hydrochloride
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
T2594 Dextromilnacipran 96847-55-1 99.9%
Dextromilnacipran
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.
T0678 Amitriptyline hydrochloride 549-18-8 99.87%
Amitriptyline hydrochloride
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive ...
T1580 Desvenlafaxine 93413-62-8 99.86%
Desvenlafaxine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reu...
T68070 Fezolamine 80410-36-2 99.85%
Fezolamine
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal upta...
T60325 Viloxazine 46817-91-8 99.82%
Viloxazine
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards...
T68095 Losulazine 72141-57-2 99.80%
Losulazine
Losulazine is a peripheral sympathetic antihypertensive compound that can be taken orally. Losulazine causes relatively modest, transient depletion of dopamine a...
T0869 Atomoxetine hydrochloride 82248-59-7 99.8%
Atomoxetine hydrochloride
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine r...
T1327 Nortriptyline hydrochloride 894-71-3 99.71%
Nortriptyline hydrochloride
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
T2575 Guanethidine sulfate 645-43-2 99.67%
Guanethidine sulfate
Guanethidine sulfate is an antihypertensive drug that reduces the release of catecholamines.
T10758L Centanafadine hydrochloride 923981-14-0 99.66%
Centanafadine hydrochloride
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC...
T22240 Amitriptyline 50-48-6 99.64%
Amitriptyline
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neurop...
T6963 Reboxetine mesylate 98769-84-7 99.64%
Reboxetine mesylate
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
Methyl reserpate
T33342L
Methyl reserpate (NSC 81464), a yohimbine-type alkaloid derived from the roots and leaves of Rauwolfia vomitoria, inhibits the transport of norepinephrine into c...
Reboxetine
T2579
Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) sa...
Ampreloxetine
T26622
Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.
Atomoxetine
T20886
Atomoxetine (HSDB 7352) is a selective norepinephrine inhibitor that may cause an increase in blood pressure by increasing norepinephrine concentrations in perip...
Phenelzine
T9540
Phenelzine is an antidepressant and mania drug, which is a monoamine oxidase inhibitor. Its antidepressant effect is similar to that of niacinamide. It can reduc...
Duloxetine hydrochloride
T1471
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE...
Ziprasidone hydrochloride monohydrate
T0031
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic ac...
Doxepin hydrochloride
T1540
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
Dextromilnacipran
T2594
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.
Amitriptyline hydrochloride
T0678
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive ...
Desvenlafaxine
T1580
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reu...
Fezolamine
T68070
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal upta...
Viloxazine
T60325
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards...
Losulazine
T68095
Losulazine is a peripheral sympathetic antihypertensive compound that can be taken orally. Losulazine causes relatively modest, transient depletion of dopamine a...
Atomoxetine hydrochloride
T0869
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine r...
Nortriptyline hydrochloride
T1327
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
Guanethidine sulfate
T2575
Guanethidine sulfate is an antihypertensive drug that reduces the release of catecholamines.
Centanafadine hydrochloride
T10758L
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC...
Amitriptyline
T22240
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neurop...
Reboxetine mesylate
T6963
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
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TargetMol