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Neuroscience Norepinephrine

Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine is a catecholamine and a phenethylamine. Its structure differs from that of epinephrine only in that epinephrine has a methyl group attached to its nitrogen, whereas the methyl group is replaced by a hydrogen atom in norepinephrine. The prefix nor- is derived as an abbreviation of the word "normal", used to indicate a demethylated compound.
Cat No. product name
T23070 Nisoxetine hydrochloride Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
T6188 Desvenlafaxine succinate hydrate Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
T0172 Maprotiline hydrochloride Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, i...
T0031L Ziprasidone hydrochloride Ziprasidone (hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T1540 Doxepin hydrochloride Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mec...
T0185 Escitalopram Escitalopram is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol upt...
T1471 Duloxetine hydrochloride Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSI...
T0031 Ziprasidone hydrochloride monohydrate Ziprasidone(CP88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
T0031L2 Ziprasidone Ziprasidone is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T0255 Clomipramine hydrochloride Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily abs...
T0783 Mianserin hydrochloride Mianserin hydrochloride is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin ...
T0785 Dexchlorpheniramine Maleate Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria...
T1308 Orphenadrine hydrochloride Orphenadrine hydrochloride is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T1735 Lurasidone hydrochloride Lurasidone hydrochloride is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor...
T2092 Amitifadine hydrochloride Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T10758L Centanafadine hydrochloride Centanafadine hydrochloride is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 8...
T0878 Diosmin Diosmin is a bioflavonoid that strengthens vascular walls.
T1045 Trimipramine maleate Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin a...
T0678 Amitriptyline hydrochloride Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T2575 Guanethidine Monosulfate Guanethidine is an antihypertensive drug that reduces the release of catecholamines.
T3526 Dasotraline hydrochloride Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor  that inhibits dopamine, norepinephrine, and serotonin transporters with IC...
T2579 Reboxetine Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sol...
T0869 Atomoxetine hydrochloride Atomoxetine Hydrochloride is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant,  norepinephrine reuptake...
T1327 Nortriptyline hydrochloride Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia,...
T1580 Desvenlafaxine Desvenlafaxine is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) a...
T2594 Levomilnacipran Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor.
T6963 Reboxetine mesylate Reboxetine is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
T5380 Ansofaxine hydrochloride Ansofaxine (LY03005; LPM570065) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).
T7583 Solriamfetol Solriamfetol is a new selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects.
T1189 Milnacipran hydrochloride Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Levomilnacipran is an enantiomer of milnacipran, ...
Nisoxetine hydrochloride
T23070CAS 57754-86-6
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
Desvenlafaxine succinate hydrate
T6188CAS 386750-22-7
Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
Maprotiline hydrochloride
T0172CAS 10347-81-6
Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, i...
Ziprasidone hydrochloride
T0031LCAS 122883-93-6
Ziprasidone (hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
Doxepin hydrochloride
T1540CAS 1229-29-4
Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mec...
Escitalopram
T0185CAS 128196-01-0
Escitalopram is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol upt...
Duloxetine hydrochloride
T1471CAS 136434-34-9
Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSI...
Ziprasidone hydrochloride monohydrate
T0031CAS 138982-67-9
Ziprasidone(CP88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
Ziprasidone
T0031L2CAS 146939-27-7
Ziprasidone is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
Clomipramine hydrochloride
T0255CAS 17321-77-6
Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily abs...
Mianserin hydrochloride
T0783CAS 21535-47-7
Mianserin hydrochloride is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin ...
Dexchlorpheniramine Maleate
T0785CAS 2438-32-6
Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria...
Orphenadrine hydrochloride
T1308CAS 341-69-5
Orphenadrine hydrochloride is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Lurasidone hydrochloride
T1735CAS 367514-88-3
Lurasidone hydrochloride is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor...
Amitifadine hydrochloride
T2092CAS 410074-74-7
Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
Centanafadine hydrochloride
T10758LCAS 923981-14-0
Centanafadine hydrochloride is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 8...
Diosmin
T0878CAS 520-27-4
Diosmin is a bioflavonoid that strengthens vascular walls.
Trimipramine maleate
T1045CAS 521-78-8
Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin a...
Amitriptyline hydrochloride
T0678CAS 549-18-8
Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
Guanethidine Monosulfate
T2575CAS 645-43-2
Guanethidine is an antihypertensive drug that reduces the release of catecholamines.
Dasotraline hydrochloride
T3526CAS 675126-08-6
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor  that inhibits dopamine, norepinephrine, and serotonin transporters with IC...
Reboxetine
T2579CAS 71620-89-8
Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sol...
Atomoxetine hydrochloride
T0869CAS 82248-59-7
Atomoxetine Hydrochloride is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant,  norepinephrine reuptake...
Nortriptyline hydrochloride
T1327CAS 894-71-3
Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia,...
Desvenlafaxine
T1580CAS 93413-62-8
Desvenlafaxine is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) a...
Levomilnacipran
T2594CAS 96847-55-1
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor.
Reboxetine mesylate
T6963CAS 98769-84-7
Reboxetine is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).
Ansofaxine hydrochloride
T5380CAS 916918-84-8
Ansofaxine (LY03005; LPM570065) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).
solriamfetol
T7583CAS 178429-62-4
Solriamfetol is a new selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects.
Milnacipran hydrochloride
T1189CAS 101152-94-7
Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Levomilnacipran is an enantiomer of milnacipran, ...