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Melanin-concentrating Hormone Receptor (MCHR)

Two Melanin-concentrating hormone receptors (MCHR) have recently been characterized: MCH-R1 and MCH-R2. These two receptors share approximately 38% homology. MCH-R1 is expressed in all mammals.MCH-R2 is only found in some primates and carnivores including dogs, ferrets and humans.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T22591 ATC 0175 hydrochloride 510733-97-8 99.84%
ATC 0175 hydrochloride
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affini...
TP1996 MCH(human, mouse, rat) 128315-56-0 99.55%
MCH(human, mouse, rat)
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 an...
TP1104L Melanin Concentrating Hormone, salmon acetate 99.41%
Melanin Concentrating Hormone, salmon acetate
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
TP1997L [Ala17]-MCH acetate 98.92%
[Ala17]-MCH acetate
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR...
T13101 TC-MCH 7c 864756-35-4 98.8%
TC-MCH 7c
TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpy...
TP1953L PG 931 acetate 98.74%
PG 931 acetate
PG 931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.
TP1578L Neuropeptide EI, rat acetate 95.55%
Neuropeptide EI, rat acetate
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
T8004 SNAP 94847 hydrochloride 1781934-47-1 100%
SNAP 94847 hydrochloride
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
T5406 SNAP 94847 487051-12-7
SNAP 94847
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces ...
T11966 MCHR1 antagonist 2 863115-70-2 98%
MCHR1 antagonist 2
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
ATC 0175 hydrochloride
T22591
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affini...
MCH(human, mouse, rat)
TP1996
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 an...
Melanin Concentrating Hormone, salmon acetate
TP1104L
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
[Ala17]-MCH acetate
TP1997L
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR...
TC-MCH 7c
T13101
TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpy...
PG 931 acetate
TP1953L
PG 931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.
Neuropeptide EI, rat acetate
TP1578L
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
SNAP 94847 hydrochloride
T8004
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
SNAP 94847
T5406
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces ...
MCHR1 antagonist 2
T11966
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
TargetMol