Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.

Cat. No.	Product name	CAS No.	Purity
T4571	Balsalazide	80573-04-2	98%
T4571	Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
TN4379	Kansuinine A	57701-86-7	98%
TN4379	Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
T10389	Aspartyl-alanyl-diketopiperazine	110954-19-3	98%
T10389	Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
T36526	IL-17 modulator 4	2446803-65-0	98%
T36526	IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
T9911	Tocilizumab	375823-41-9
T9911	Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T0054	Disulfiram	97-77-8
T0054	Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the interme...
T9913	Ustekinumab	815610-63-0
T9913	Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T13375	YQ128	2454246-18-3
T13375	YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T8033	Sodium Thiocyanate	540-72-7
T8033	Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
TQ0181	Resatorvid	243984-11-4	100%
TQ0181	Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n...
T0304	Methylthiouracil	56-04-2	100%
T0304	Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T6S2140	β-Anhydroicaritin	38226-86-7	96.95%
T6S2140	1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
T8867	RO2959 Hydrochloride	1219927-22-6	97.42%
T8867	RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T5641	RP-54745	135330-08-4	98%
T5641	RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
T2061	APY0201	1232221-74-7	98%
T2061	APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
T6761	Ossirene	106566-58-9	98%
T6761	AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T1273	Diacerein	13739-02-1	98.14%
T1273	Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res...
TN1291	7,3',4'-Tri-O-methylluteolin	29080-58-8	98.66%
TN1291	5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC val...
T4602	Hydrocortisone hemisuccinate	2203-97-6	98.7%
T4602	Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T14778	BRD6989	642008-81-9	98.82%
T14778	BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...