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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.
Cat. No. Product name CAS No. Purity Chemical Structure
T4571 Balsalazide 80573-04-2 98%
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
T2S0843 Negletein 29550-13-8 98%
1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action...
T4403 AX-024 hydrochloride 1704801-24-0 98%
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interfer...
T8280 Deacetylasperulosidic Acid 14259-55-3 98%
Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also pr...
T4450 GIBH-130 1252608-59-5 98%
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
T6S1538 Neochlorogenic acid 906-33-2 98%
(E)-Neochlorogenic Acid is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T3829 Ginsenoside F3 62025-50-7 98%
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
T3533 Apilimod mesylate 870087-36-8 98%
Apilimod mesylate is a potent IL-12/IL-23 inhibitor.
T9157 GP130 receptor agonist-1 339303-87-6 98%
N-(4-Fluorophenyl)-4-phenyl-2-thiazolami is a potent, brain-penetrant and orally active GP130 receptor agonist.
T3133 YM-90709 163769-88-8 98%
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
T2S0342 Armillarisin A 53696-74-5 98%
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
T2720 Ginsenoside Rc 11021-14-0 98%
Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T2601 Vidofludimus 717824-30-1 98%
Vidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T10389 Aspartyl-alanyl-diketopiperazine 110954-19-3 98%
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
T2791 Pectolinarin 28978-02-1 98%
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T2758 Madecassic acid 18449-41-7 98%
Madecassic acid is extracted from the whole herb of Centella asiatica.
T0117 Suplatast (Tosilate) 94055-76-2 98%
Suplatast Tosilate is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
T11634 IL-15-IN-1 1831830-20-6 98%
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
T1846 Y-320 288250-47-5 98%
Y-320 is a new phenylpyrazoleanilide immunomodulator.
T2932 Ginsenoside Rh1 63223-86-9 98%
Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
Balsalazide
T4571
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
Negletein
T2S0843
1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action...
AX-024 hydrochloride
T4403
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interfer...
Deacetylasperulosidic Acid
T8280
Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also pr...
GIBH-130
T4450
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
Neochlorogenic acid
T6S1538
(E)-Neochlorogenic Acid is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
Ginsenoside F3
T3829
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
Apilimod mesylate
T3533
Apilimod mesylate is a potent IL-12/IL-23 inhibitor.
GP130 receptor agonist-1
T9157
N-(4-Fluorophenyl)-4-phenyl-2-thiazolami is a potent, brain-penetrant and orally active GP130 receptor agonist.
YM-90709
T3133
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
Armillarisin A
T2S0342
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
Ginsenoside Rc
T2720
Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
Vidofludimus
T2601
Vidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
Aspartyl-alanyl-diketopiperazine
T10389
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
Pectolinarin
T2791
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
Madecassic acid
T2758
Madecassic acid is extracted from the whole herb of Centella asiatica.
Suplatast (Tosilate)
T0117
Suplatast Tosilate is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
IL-15-IN-1
T11634
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
Y-320
T1846
Y-320 is a new phenylpyrazoleanilide immunomodulator.
Ginsenoside Rh1
T2932
Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
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