T79513 |
ABCG2-IN-1
|
2559759-40-7
|
98%
|
|
ABCG2-IN-1 (compound K2), an analog of Ko143, constitutes an orally active inhibitor targeting ABCG2 with an inhibitory concentration (IC50) of 0.13 μM. Demonstr...
|
T79514 |
ABCG2-IN-2
|
2559759-59-8
|
98%
|
|
ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug resist...
|
TN3150 |
6,8-Diprenylnaringenin
|
68236-11-3
|
98%
|
|
6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor...
|
T15355 |
Fumitremorgin C
|
118974-02-0
|
98%
|
|
Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.
|
T4337 |
PCI 29732
|
330786-25-9
|
99.79%
|
|
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
|
T3581 |
KS176
|
1253452-78-6
|
99.55%
|
|
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MR...
|
T22680 |
CP-100356 hydrochloride
|
142715-48-8
|
99.19%
|
|
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory ef...
|
T2657 |
Elacridar
|
143664-11-3
|
99.15%
|
|
Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor.
|
T67821 |
GS-9191 PM
|
|
99.02%
|
|
GS-9191 PM is a novel antitumorviral compound, a bis-amide prodrug of the nucleotide analog 9-(2-phosphonomethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cPrPMED...
|
TQ0186 |
Ko 143
|
461054-93-3
|
98.91%
|
|
Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).
|
T13383 |
Zamicastat
|
1080028-80-3
|
97.43%
|
|
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
|
T3208 |
Brevianamide F
|
38136-70-8
|
97.30%
|
|
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess i...
|
T13365 |
YHO-13351 free base
|
912288-64-3
|
100%
|
|
YHO-13351 free base is the water-soluble prodrug of YHO-13177 which is an inhibitor of BCRP .
|
T4595 |
YHO-13177
|
912287-56-0
|
98%
|
|
YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel r...
|
T38400 |
Triclabendazole sulfoxide
|
100648-13-3
|
98%
|
|
Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibi...
|