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BCRP

The breast cancer resistance protein (BCRP), this protein functions as a xenobiotic transporter which may play a role in multi-drug resistance to chemotherapeutic agents including mitoxantrone and camptothecin analogues.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79513 ABCG2-IN-1 2559759-40-7 98%
ABCG2-IN-1
ABCG2-IN-1 (compound K2), an analog of Ko143, constitutes an orally active inhibitor targeting ABCG2 with an inhibitory concentration (IC50) of 0.13 μM. Demonstr...
T79514 ABCG2-IN-2 2559759-59-8 98%
ABCG2-IN-2
ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug resist...
TN3150 6,8-Diprenylnaringenin 68236-11-3 98%
6,8-Diprenylnaringenin
6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor...
T15355 Fumitremorgin C 118974-02-0 98%
Fumitremorgin C
Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.
T4337 PCI 29732 330786-25-9 99.79%
PCI 29732
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
T3581 KS176 1253452-78-6 99.55%
KS176
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MR...
T2657 Elacridar 143664-11-3 99.32%
Elacridar
Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor.
T22680 CP-100356 hydrochloride 142715-48-8 99.19%
CP-100356 hydrochloride
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory ef...
T67821 GS-9191 PM 99.02%
GS-9191 PM
GS-9191 PM is a novel antitumorviral compound, a bis-amide prodrug of the nucleotide analog 9-(2-phosphonomethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cPrPMED...
TQ0186 Ko 143 461054-93-3 98.91%
Ko 143
Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).
T13383 Zamicastat 1080028-80-3 97.43%
Zamicastat
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
T3208 Brevianamide F 38136-70-8 97.30%
Brevianamide F
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess i...
T13365 YHO-13351 free base 912288-64-3 100%
YHO-13351 free base
YHO-13351 free base is a water-soluble prodrug of YHO-13177, an inhibitor of BCRP.
T4595 YHO-13177 912287-56-0 98%
YHO-13177
YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel r...
T38400 Triclabendazole sulfoxide 100648-13-3 98%
Triclabendazole sulfoxide
Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibi...
ABCG2-IN-1
T79513
ABCG2-IN-1 (compound K2), an analog of Ko143, constitutes an orally active inhibitor targeting ABCG2 with an inhibitory concentration (IC50) of 0.13 μM. Demonstr...
ABCG2-IN-2
T79514
ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug resist...
6,8-Diprenylnaringenin
TN3150
6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor...
Fumitremorgin C
T15355
Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.
PCI 29732
T4337
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
KS176
T3581
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MR...
Elacridar
T2657
Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor.
CP-100356 hydrochloride
T22680
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory ef...
GS-9191 PM
T67821
GS-9191 PM is a novel antitumorviral compound, a bis-amide prodrug of the nucleotide analog 9-(2-phosphonomethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cPrPMED...
Ko 143
TQ0186
Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).
Zamicastat
T13383
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73....
Brevianamide F
T3208
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess i...
YHO-13351 free base
T13365
YHO-13351 free base is a water-soluble prodrug of YHO-13177, an inhibitor of BCRP.
YHO-13177
T4595
YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel r...
Triclabendazole sulfoxide
T38400
Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibi...
TargetMol