tail — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83174	Activated EG3 Tail
	Activated EG3 Tail facilitates the synthesis of exon-skipping oligomer conjugates that target specific sites within the human anti-muscular atrophy protein gene, promoting exon 51 skipping. This compound holds potential ...
T77269	C13-113-tetra-tail
	C13-113-tetra tail, a cationic lipid-like compound, features a polar amino alcohol head group, a tertiary amine linker, and four hydrophobic carbon-13 tails. It can be formulated into a lipid nanoparticle (LNP).
T77266	C13-112-tri-tail
	C13-112-tri-tail, a cationic lipid-like compound, features a polar amino alcohol head group, three hydrophobic 13-carbon tails, and a PEG2 linker, allowing for formulation into lipid nanoparticles (LNP).
T77268	C13-112-tetra-tail
	C13-112-tetra-tail, a cationic lipid-like compound, features a polar amino alcohol head group, four hydrophobic C13 tails, and a PEG2 linker, making it suitable for formulation into lipid nanoparticles (LNPs).
T77267	C13-113-tri-tail
	C13-113-tri tail, a cationic lipid-like compound, features a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. It is capable of being formulated into a lipid nanoparticle (LN...
T1909	L-701324	L701324	NMDAR , iGluR
	L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.		NMDAR , iGluR
T1496	Amiodarone hydrochloride	Amiodar,Amiodarone HCl,Nexterone	Potassium Channel , Adrenergic Receptor , Autophagy
	Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM C...		Potassium Channel , Adrenergic Receptor , Autophagy
T2141	Mecamylamine hydrochloride	Inversine,Mevasin	AChR
	Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.		AChR
T10337	Antimicrobial Compound 1		Antibacterial
	Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli.		Antibacterial
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T31475	Dihydropteroyl hexaglutamate
	Dihydropteroyl hexaglutamate is a link binding together sub-structures of the tail of Escherichia coli bacteriophage T4.
T38210	Hodgkinsine B
	Hodgkinsine B is an alkaloid and isomer of hodgkinsine that has analgesic activity.1It increases the latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 10 mg/kg. 1.Kodanko, J.J., Hie...
T38209	Hodgkinsine
	Hodgkinsine is a pyrrolidinoindoline alkaloid that has been found inP. colorataand has analgesic activity.1It increases latency to paw licking in the hot plate test and latency to tail withdrawal in the tail-flick test i...
T69413	Primordazine B
	Primordazine B is a selective inhibitor of primordial germ cell (PGC) development which targets poly(A)-tail-independent noncanonical translation (PAINT).
T35419	τ-Fluvalinate
	τ-Fluvalinate is a pyrethroid acaricide.1It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed inXenopusoocytes (EC50= 60 nM). It also induces tail currents in honey...
T73742	98N12-5
	98N12-5, a novel multi-tail ionizable lipid, demonstrates efficient in vivo siRNA delivery to the liver.
T69857	DB293
	DB293 is an inhibitor of PIT-1 and BRN-3 transcription factors. DB293 binds as head-to-tail stacked dimers in the minor groove of 5'-ATGA sequence, thereby leading to an increase in the size of minor groove.
T39286	Br-PBTC
	Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs). It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes of nAChRs, ...
T71586	Z-VAE(OMe)-fmk
	Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-t...
T75954	Mambalgin 1 TFA
	Mambalgin 1 TFA, a selective inhibitor of ASIC1a (with IC50 values of 192 nM for human ASIC1a and 72 nM for the ASIC1a/1b dimer), preferentially binds to the channel in its closed/inactive state. It demonstrates selectiv...