tace

Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but also antiestrogenic activities.

IK-862 is a selective inhibitor of TACE (ADAM17).

BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.

GW280264X (Carbamic acid) is an inhibitor of ADAM17 .

TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.

Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate.

Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.

Etacelasil (CGA 13586) is a compound that releases ethylene upon contact with water. It facilitates the abscission of olive fruits.

Ramentaceone is an antineoplastic.

Belatacept (BMS 224818) is a selective blocker of T-cell costimulation that binds to CD 80/86 ligands, inhibiting CD-28-mediated T-cell activation. It is useful for studying immunosuppression in organ transplantation.

Crustacean cardioactive peptide，Cyclic (CCAP) is a nine-amino-acid insect cardioregulatory peptide, initially isolated from Manduca sexta (the tobacco hawkmoth). It contains cysteines at positions 3 and 9 that form a disulfide bridge, and its carboxyl-terminus is amidated [1].

Astacene is a key secondary carotenoid that can be extracted from the skin of goldfish and other species. It is an oxidation product of astaxanthin. Carotenoids possess significant biological activity and may play a role in cellular differentiation, growth regulation, photoprotection, membrane stability, photosynthesis, vision processes, and nutrition.

Crustacean Cardioactive Peptide (CCAP) is a highly conserved modified cyclic nonapeptide with a primary structure of PFCNAFTGC-NH2, a disulfide bridge between Cys3 and Cys9, which acts as a cardiac gas pedal, neuropeptide transmitter, and hormone with cardiac, adipotropic hormone, and metabolic regulatory effects, reproductive system.

Crustacean Cardioactive Peptide Acetate (CCAP acetate) is is the most conserved and ubiquitous neuropeptide in arthropods and is produced in insects by a network of conserved neurons in the ventral nerve cord.Crustacean Cardioactive Peptide Acetate is a cyclic amidated natriuretic peptide hormone commonly found in insects, crustaceans and other arthropods.

p-Nitrophenyl β-D-cellobioside heptacetate is a biochemical reagent used in glycobiology research. Glycobiology focuses on the study of the structure, synthesis, biology, and evolution of sugars. This field encompasses carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. It is closely linked to basic research, biomedicine, and biotechnology.

Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.

GNF4877 is a potent inhibitor of DYRK1A and GSK3β (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased β-cell proliferation.

Metaldehyde (Metacetaldehyde) is an agriculturally used molluscicide that induces DNA fragmentation in cells.

Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.

D-(+)-Cellobiose (Cellobiose) is a disaccharide, a reducing sugar, consists of two β-glucose molecules linked by a β(1→4) bond. It can be hydrolyzed to glucose enzymatically or with acid.

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor with potential anti-inflammatory activity. It mitigates statin-induced toxicity in human skeletal muscle cells and protects guinea pigs from simvastatin-induced myotoxicity, useful for research on hypercholesterolemia and HMG-CoA reductase deficiency.

Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action

Enterostatin, human, mouse, rat acetate is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase.