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t b4

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TMSB4X Protein, Human, Recombinant
TMSB4X, TMSB4, Thymosin beta-4, THYB4, TB4X, T beta-4, Fx
TMPH-04156
Expression system: E. coli
Length: 2-44, Full Length of Mature Protein
Activity: Cell Activity
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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CD19 Protein, Rhesus macaque, Recombinant (hFc)
T-Cell Surface Antigen Leu-12, Differentiation Antigen CD19, CD19, B-Lymphocyte Surface Antigen B4, B-Lymphocyte Antigen CD19
TMPJ-00329
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer