mmad

MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).

Mc-MMAD is monomethyl auristatin D (MMAD) modified with the protective group maleimidocaproyl (Mc). MMAD is a potent tubulin microtubule inhibitor that suppresses cancer cell proliferation and is commonly employed as a toxic payload in ADC synthesis.

Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs to deliver the cytotoxic agent MMAD specifically to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects.

MC-VA-PAB-MMAD is a thiol-reactive Drug-linker. MMAD is an effective microtubule (tubulin) inhibitor, which is commonly used in the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG4-VC-PAB-MMAD is a click-reactive Drug-linker that contains a DBCO group and can undergo a strain-promoted acetylene-nitride cycloaddition reaction (SPAAC) with molecules containing an Azide group. MMAD is an effective microtubule (tubulin) inhibitor. DBCO-PEG4-VC-PAB-MMAF, DBCO-PEG4-VC-PAB-MMAD can be used in the synthesis of antibody-drug conjugates (ADC).

OSu-Glu-VC-PAB-MMAD is an agent-linker conjugate used in antibody-drug conjugates (ADCs) with potent antitumor activity. It features MMAD, a powerful tubulin inhibitor, linked via the cleavable ADC linker OSu-Glu-VC-PAB, enabling targeted cancer therapy.

MC-VC-PAB-MMAD is a conjugate for antibody-drug conjugates (ADCs) that exhibits potent antitumor activity by employing MMAD, a powerful tubulin inhibitor, connected through the cleavable ADC linker MC-VC-PAB [1].

MMAD-d8 is the deuterated form of MMAD.

D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.

Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.

Cys-mcMMAD is a drug-linker conjugate for ADC (antibody-drug conjugate) featuring MMAD, a potent tubulin inhibitor.

Amogammadex acts as an antagonist for the neuromuscular blockers rocuronium and vecuronium.

Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periph

γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.

3-Methyl-2-buten-1-ol (gamma-dimethylallylalcohol) is found in blackcurrant, ylang-ylang, hop oils, orange peel oil, and various fruits such as orange, lemon, lime, grape, pineapple, purple passion fruit, and loganberry. Prenol is a flavoring ingredient.

Gamma-decalactone (Decan-4-olide) is a food additive with a fruity peach flavor. Ricinoleic acid (12-hydroxy-octadec-9-enoic acid) is often used as a substrate in the production of γ-Decalactone.

Gamma-Dodecalactone is a furan derivative widely used in biochemical experiments and drug synthesis research.

gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.

Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulatory peptide with antibacterial activity that inhibits the homodimerization of STAT3 in the cytoplasm, thereby inhibiting STAT3 signaling. It can be used for studying immune-sensitive diseases and HCV infections.

Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage function, and inhibits STAT3 signaling.Golotimod has been used in the study of recurrent genital Herpes Simplex Virus 2 (HSV-2) infection and oral mucositis.

Golotimod TFA (SCV 07 TFA) is a dipeptide exhibiting immunomodulatory and antibacterial activity. It reduces recurrent lesions caused by HSV-2, alleviates radiation-induced oral mucositis, and inhibits the homodimerisation of STAT3 molecules in the cytoplasm.

gamma-DGG is a competitive blocker of AMPA receptor.

Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.

Anti-Mouse TCR gamma/delta Antibody is an IgG class inhibitor derived from the host Armenian Hamster, targeting the mouse TCR gamma/delta receptor.