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Search Results for " inflammasome "

Targets

62

Compounds

11

Natural Products

16

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3230 NLRP3-IN-2 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I NOD-like Receptor (NLR) , NOD
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i...
T15052 Dapansutrile NOD-like Receptor (NLR) , NOD
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T8828 CP 424174 IL Receptor
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
T0948 Adrenalone hydrochloride Adrenalone HCl Adrenergic Receptor
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc...
T1902 BAY 11-7082 BAY 11-7821 Apoptosis , Others , IκB/IKK , DUB , Autophagy
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM). BAY 11-7082 is also an inhibitor of the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
T28178 NLRP3-IN-9 INF-4E,INF 4E,INF4E NOD
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...
T1404 Stavudine d4T,Sanilvudine,BMY-27857,NSC 163661 Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T0342 Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate) VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T20731 Brilliant blue G-250 BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G P2X Receptor
Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) is an antagonist of the P2X7 purinergic receptor.
T9222 Emlenoflast MCC7840 NOD-like Receptor (NLR) , NOD
Emlenoflast (MCC7840) is a potent and selective inhibitor of NLRP3 inflammasome.
T28281 OXSI-2 OXSI 2,Syk Inhibitor Syk
OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets.
T25548 JC124 JC 124,JC-124 NOD
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
T8553 BC-1471 Others
BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].
T27841 Lobeglitazone Sulfate CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang NOD
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2...
T11662L INT-777 S-EMCA GPCR19
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats...
T60404 NLRP3/AIM2-IN-2 AIM2
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent pyroptosis with IC50 of 0.2392 ± 0.0233 μ M.
T13375 YQ128 IL Receptor , NOD-like Receptor (NLR) , NOD , Interleukin
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T61392 NLRP3-IN-10 ZVN26391 NOD
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
T3701 MCC950 CP-456773 NOD
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and...
T60442 NLRP3/AIM2-IN-3 NOD , AIM2
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of N...
T77675 TNKS-2-IN-1 PARP , Wnt/beta-catenin , Antibiotic
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas...
T9222L Emlenoflast sodium MCC7840 sodium NOD
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome, and can be used in the study of inflammatory diseases.
T78168 NLRP3-IN-17 NOD-like Receptor (NLR)
NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for...
T38360 NBC 19
Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release. Baldwin et al (2017) Boron-Based Inhibitors of the NLRP3 Inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355 |Red...
T26432 A68930 A 68930,A70108,A-68930,A 70108,A-70108
A 68930 is a dopamine D-1 receptor antagonist. A 68930 inhibits NLRP3 inflammasome activity.
T78894 NLRP3-IN-21 NOD-like Receptor (NLR)
NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties. It suppresses the activation of the NLRP3 inflammasome and pyroptosis by inhibiting gasdermin D cleavage, ...
T62809 NLRP3-IN-7
NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.
T71314 GL-V9
GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.
T61826 NLRP3-IN-4
NLRP3-IN-4 is a highly efficient and orally bioavailable inhibitor of NLRP3 inflammasome, which exhibits strong anti-inflammatory properties specifically targeted towards colitis.
T10447 BAA473 Others
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial c...
T62808 NLRP3-IN-6
NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.
T71651 GSK1370319A
GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and caspase 1 activation in lipopolysaccharide (LPS)-primed mixed glia by blocking assembly of the infla...
T39552 NLRP3-IN-5 NLRP3-IN-5
NLRP3-IN-5, a compound disclosed in WO2016131098, is an inhibitor of NLRP3 inflammasome. It consists of the chemical structure N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2-l)furan-2-sulfonamide.
T78613 Selnoflast calcium RO-7486967 calcium NOD-like Receptor (NLR)
Selnoflast calcium (example 6), an NLRP3 inhibitor[1], is a chemical compound designed to suppress the activity of the NLRP3 inflammasome.
T38106 JC-171
JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activatio...
T9655 NBC 6
NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor with IC50 of 574 nM. NLRP3-IN-NBC6 acts independently of Ca 2+. NLRP3-IN-NBC6 inhibits Nigericin -induced inflammasome activation in THP-1 cells and Imiqu...
T78822 JT002 NOD-like Receptor (NLR)
JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18) and pyroptosis, as well as inhibits the formation of the NLR...
T68225 Fc 11a-2
Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-...
T81665 NLRP3-IN-23 NOD-like Receptor (NLR)
NLRP3-IN-23 (Compound 15C) is an inhibitor that significantly impedes heme-mediated activation of the NLRP3 inflammasome at a concentration of 0.1 μM [1].
T73015 NLRP3-IN-16 NOD-like Receptor (NLR)
NLRP3-IN-16 is a potent, selective inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release with an IC50 of 0.065 μM, and is primarily utilized in inflammation research [1].
T73014 NLRP3-IN-15
NLRP3-IN-15 is a potent and selective NLRP3 inflammasome inhibitor. NLRP3-IN-15 inhibits IL-1β release with an IC 50 of 0.114 μM. NLRP3-IN-15 can be used for the research of inflammation .
T78639 Oxidized ATP trisodium salt oATP trisodium salt P2X Receptor
Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (CRP)-induced NLRP3 inflammasome activation. It is utilized i...
T73013 NLRP3-IN-14
NLRP3-IN-14 is a potent and selective NLRP3 inflammasome inhibitor ( K D : 5.87 μM). NLRP3-IN-14 inhibits IL-1β release with an IC 50 of 0.131 μM. NLRP3-IN-14 can be used for the research of inflammation .
T76111 Hexokinase (ScHEX1)
Hexokinase (ScHEX1) is a glycolytic enzyme hexokinase that is inhibited by n-acetylglucosamine. Inhibition of Hexokinase (ScHEX1) by n-acetylglucosamine leads to its separation from the mitochondrial outer membrane, resu...
T73034 NLRP3-IN-12
NLRP3-IN-12 is a specific NLRP3 inflammasome inhibitor. NLRP3-IN-12 reduces the release of IL-1β by targeting the NLRP3 protein, with an IC 50 of 0.45 μM. NLRP3-IN-12 can be used for the research of inflammatory bowel di...
T78061 Peptide5 TFA Gap Junction Protein
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it suppresses the NLRP3 inflammasome, functioning as an anti-in...
T79585 Anti-inflammatory agent 50 NF-κB
Anti-inflammatory agent 50 (compound a1), a derivative of Fusidic acid, exerts its effects through inhibition of inflammatory mediators including NO, IL-6, and TNF-α. It mitigates acute lung injury by modulating these me...
T69745 GDC-2394
GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC 50 s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLR...
T79695 NLRP3-IN-19 NLRP3-IN-19 NOD-like Receptor (NLR)
JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome. This action results in the suppression of cytokine release and prevention of pyroptosis. J...
T79696 JT001 sodium NLRP3-IN-19 sodium NOD-like Receptor (NLR)
JT001 (NLRP3-IN-19) sodium is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, thus curbing cytokine release and averting pyroptosis. It is utilized in research f...

Compounds

NLRP3-IN-2
T3230
Synonym: 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I
Target: NOD-like Receptor (NLR), NOD
Dapansutrile
T15052
Synonym:
Target: NOD-like Receptor (NLR), NOD
CP 424174
T8828
Synonym:
Target: IL Receptor
Adrenalone hydrochloride
T0948
Synonym: Adrenalone HCl
Target: Adrenergic Receptor
BAY 11-7082
T1902
Synonym: BAY 11-7821
Target: Apoptosis, Others, IκB/IKK, DUB, Autophagy
NLRP3-IN-9
T28178
Synonym: INF-4E,INF 4E,INF4E
Target: NOD
Stavudine
T1404
Synonym: d4T,Sanilvudine,BMY-27857,NSC 163661
Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, NOD-like Receptor (NLR), Reverse Transcriptase, Autophagy
Carvedilol phosphate hemihydrate
T0342
Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)
Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy
Brilliant blue G-250
T20731
Synonym: BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G
Target: P2X Receptor
Emlenoflast
T9222
Synonym: MCC7840
Target: NOD-like Receptor (NLR), NOD
OXSI-2
T28281
Synonym: OXSI 2,Syk Inhibitor
Target: Syk
JC124
T25548
Synonym: JC 124,JC-124
Target: NOD
BC-1471
T8553
Synonym:
Target: Others
Lobeglitazone Sulfate
T27841
Synonym: CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang
Target: NOD
INT-777
T11662L
Synonym: S-EMCA
Target: GPCR19
NLRP3/AIM2-IN-2
T60404
Synonym:
Target: AIM2
YQ128
T13375
Synonym:
Target: IL Receptor, NOD-like Receptor (NLR), NOD, Interleukin
NLRP3-IN-10
T61392
Synonym: ZVN26391
Target: NOD
MCC950
T3701
Synonym: CP-456773
Target: NOD
NLRP3/AIM2-IN-3
T60442
Synonym:
Target: NOD, AIM2
TNKS-2-IN-1
T77675
Synonym:
Target: PARP, Wnt/beta-catenin, Antibiotic
Emlenoflast sodium
T9222L
Synonym: MCC7840 sodium
Target: NOD
NLRP3-IN-17
T78168
Synonym:
Target: NOD-like Receptor (NLR)
NBC 19
T38360
Synonym:
Target:
A68930
T26432
Synonym: A 68930,A70108,A-68930,A 70108,A-70108
Target:
NLRP3-IN-21
T78894
Synonym:
Target: NOD-like Receptor (NLR)
NLRP3-IN-7
T62809
Synonym:
Target:
GL-V9
T71314
Synonym:
Target:
NLRP3-IN-4
T61826
Synonym:
Target:
BAA473
T10447
Synonym:
Target: Others
NLRP3-IN-6
T62808
Synonym:
Target:
GSK1370319A
T71651
Synonym:
Target:
NLRP3-IN-5
T39552
Synonym: NLRP3-IN-5
Target:
Selnoflast calcium
T78613
Synonym: RO-7486967 calcium
Target: NOD-like Receptor (NLR)
JC-171
T38106
Synonym:
Target:
NBC 6
T9655
Synonym:
Target:
JT002
T78822
Synonym:
Target: NOD-like Receptor (NLR)
Fc 11a-2
T68225
Synonym:
Target:
NLRP3-IN-23
T81665
Synonym:
Target: NOD-like Receptor (NLR)
NLRP3-IN-16
T73015
Synonym:
Target: NOD-like Receptor (NLR)
NLRP3-IN-15
T73014
Synonym:
Target:
Oxidized ATP trisodium salt
T78639
Synonym: oATP trisodium salt
Target: P2X Receptor
NLRP3-IN-14
T73013
Synonym:
Target:
Hexokinase (ScHEX1)
T76111
Synonym:
Target:
NLRP3-IN-12
T73034
Synonym:
Target:
Peptide5 TFA
T78061
Synonym:
Target: Gap Junction Protein
Anti-inflammatory agent 50
T79585
Synonym:
Target: NF-κB
GDC-2394
T69745
Synonym:
Target:
NLRP3-IN-19
T79695
Synonym: NLRP3-IN-19
Target: NOD-like Receptor (NLR)
JT001 sodium
T79696
Synonym: NLRP3-IN-19 sodium
Target: NOD-like Receptor (NLR)
1 2
Cat No. Product Name Synonyms Targets
TQ0165 Arglabin (+)-Arglabin NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
T20089 ATP Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate Endogenous Metabolite
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...
T9352 Hydrocotarnine Others
hydrocotarnine is an inhibitor of Cbl.
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T2812 ATP disodium salt hydrate ATP disodium,ATP disodium salt,Adenosine disodium triphosphate Others , Endogenous Metabolite
ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.
T1352 ATP disodium salt Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate P2X Receptor , Endogenous Metabolite
ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist.
T6S1367 Procyanidin B2 Proanthocyanidin B2 Reactive Oxygen Species , NOD
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ...
T3092 Nigericin sodium salt Potassium Channel , NOD-like Receptor (NLR) , Antibacterial , Antibiotic , NOD
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-...
T5716 4'-Methoxyresveratrol 4'-O-Methylresveratrol advanced glycation end products
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced...
T72580 Isoandrographolide
Isoandrographolide possesses cell differentiation inducing and hepatoprotective effect. Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice .
T38838 QS-21 Stimulon,QS-21
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01564 ICA1 Protein, Human, Recombinant (His) Human Yeast
Acts as the sensor component of the NLRP1 inflammasome, which mediates inflammasome activation in response to various pathogen-associated signals, leading to subsequent pyroptosis. Inflammasomes are supramolecular comple...
TMPH-02512 TEM8/ANTXR1 Protein, Mouse, Recombinant (His) Mouse E. coli
As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polym...
TMPH-01565 IARS Protein, Human, Recombinant (His & Myc) Human E. coli
As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polym...
TMPH-00904 Adenylate kinase 7 Protein, Human, Recombinant (His) Human Baculovirus
Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-...
TMPK-00162 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-01228 MARCO Protein, Human, Recombinant (His) Human HEK293
Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in...
TMPK-00161 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-00515 IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPH-00957 ARNT Protein, Human, Recombinant (His) Human Yeast
Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well ...
TMPH-01551 IFNLR1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the in...
TMPY-01775 AIM2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPJ-00789 Flagellin Protein, Salmonella Typhimurium, Recombinant Salmonella typhimurium E. coli
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin...
TMPH-02400 Pal Protein, Legionella pneumophila, Recombinant (His) Legionella pneumophila Yeast
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-term...
TMPH-00948 APOC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-00939 Anoctamin-5/ANO5 Protein, Human, Recombinant (His) Human HEK293
G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrah...
TMPH-00949 APOLD1 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
ICA1 Protein, Human, Recombinant (His)
TMPH-01564
Species: Human
Expression System: Yeast
TEM8/ANTXR1 Protein, Mouse, Recombinant (His)
TMPH-02512
Species: Mouse
Expression System: E. coli
IARS Protein, Human, Recombinant (His & Myc)
TMPH-01565
Species: Human
Expression System: E. coli
Adenylate kinase 7 Protein, Human, Recombinant (His)
TMPH-00904
Species: Human
Expression System: Baculovirus
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00162
Species: Human
Expression System: E. coli
MARCO Protein, Human, Recombinant (His)
TMPK-01228
Species: Human
Expression System: HEK293
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
TMPK-00161
Species: Human
Expression System: E. coli
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
TMPK-00515
Species: Cynomolgus
Expression System: E. coli
ARNT Protein, Human, Recombinant (His)
TMPH-00957
Species: Human
Expression System: Yeast
IFNLR1 Protein, Human, Recombinant (His & SUMO)
TMPH-01551
Species: Human
Expression System: E. coli
AIM2 Protein, Human, Recombinant (GST)
TMPY-01775
Species: Human
Expression System: Baculovirus-Insect Cells
Flagellin Protein, Salmonella Typhimurium, Recombinant
TMPJ-00789
Species: Salmonella typhimurium
Expression System: E. coli
Pal Protein, Legionella pneumophila, Recombinant (His)
TMPH-02400
Species: Legionella pneumophila
Expression System: Yeast
APOC3 Protein, Human, Recombinant (His & SUMO)
TMPH-00948
Species: Human
Expression System: E. coli
Anoctamin-5/ANO5 Protein, Human, Recombinant (His)
TMPH-00939
Species: Human
Expression System: HEK293
APOLD1 Protein, Human, Recombinant (His)
TMPH-00949
Species: Human
Expression System: in vitro E. coli expression system
TargetMol