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Search Result

Search Results for " fluoroquinolone "

Targets

DNA gyrase Antibacterial Antibiotic

70

Compounds

5

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T0116 Balofloxacin DNA gyrase , Antibacterial , Antibiotic
Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.
T3117 Marbofloxacin Marbofloxacine,Zeniquin,Marbocyl Topoisomerase , Antibacterial , Antibiotic
Marbofloxacin (Zeniquin) is an effective, broad-spectrum antibiotic of bacterial, which inhibits DNA replication.
T9066 Merafloxacin CI 934 SARS-CoV
Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.
T6349 Sitafloxacin Hydrate DU-6859a,DU6859a hydrate Antibacterial , Antibiotic
Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.
T7865 Danofloxacin Danofloxacino,Danofloxacin free base,Danofloxacine Others , DNA/RNA Synthesis , Antibacterial , Antibiotic
Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.
T6406 Besifloxacin Hydrochloride BOL-303224-A,Besivance hydrochloride,Besifloxacin HCl Antibacterial , Antibiotic
Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.
T1095 Sparfloxacin AT-4140,PD 131501,Zagam,CI-978 DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
T1492 Gemifloxacin mesylate LB-20304a,SB-265805S,Gemifloxacin mesylate DNA gyrase , Topoisomerase , Antibacterial
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of...
T1620 Pazufloxacin Mesylate Pazucross,Pazufloxacin mesilate,T-3762,Pazufloxacin methanesulfonate Topoisomerase , Antibacterial , Antibiotic
Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.
T8142 Difloxacin hydrochloride Difloxacin HCl Antibacterial , Antibiotic
Difloxacin hydrochloride (Difloxacin HCl) is a fluoroquinolone antibiotic, is a broad-spectrum antibacterial drug.
T0292 Orbifloxacin CP-104354 Antibacterial , Antibiotic
Orbifloxacin (CP-104354) is a broad-spectrum fluoroquinolone antibiotic.
TQ0221 Rufloxacin hydrochloride MF-934 hydrochloride Antibacterial
Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial and inhibits topoisomerase. Rufloxacin hydrochloride inhibits B-cell differentiation in human mononuclear cells.
T1294 Fleroxacin AM-833,RO 23-6240 DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
T1640 Ciprofloxacin Ciproxan,Ciprobay,Bay o 9867,Bay-09867 Topoisomerase , Antibacterial , Antibiotic
Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.
T1444 Lomefloxacin SC47111A Topoisomerase , Antibacterial , Antibiotic
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
T0425 Pefloxacin Mesylate Pefloxacinium mesylate Topoisomerase , Antibacterial , Antibiotic
Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
T8173 Delafloxacin meglumine ABT492 meglumine,WQ-3034 meglumine,RX-3341 meglumine Antibacterial , Antibiotic
Delafloxacin meglumine (RX-3341 meglumine) is a broad-spectrum fluoroquinolone antibiotic.
T12649 Ibafloxacine S25930,Ibafloxacin,R835 Antifungal
Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against Bartonella.
T4063 Delafloxacin ABT492,WQ-3034,RX-3341 Antibacterial , Antibiotic
Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 μg/ml).
T8835 Tosufloxacin hydrochloride A-61827 hydrochloride,T-3262 hydrochloride Antibacterial
Tosufloxacin hydrochloride is a fluoroquinolone antibacterial agent used to treat bacterial infections.Tosufloxacin hydrochloride is also a bacterial Topo (DNA gyrase, topoisomerase)) inhibitor.
T0902 Ofloxacin DL8280,Hoe-280,Floxin,Tarivid,Oxaldin Topoisomerase , Antibacterial , Antibiotic
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting i...
T1283 Clinafloxacin PD 127391,CI-960,AM-1091 Antibacterial , Antibiotic
Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.
T0331L Moxifloxacin Avelox,Moxeza Others , Antibacterial , Antibiotic
Moxifloxacin (Avelox) is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae.
T5394 Prulifloxacin AF 3012,Pruvel,NM441 Topoisomerase , Antibacterial , Antibiotic
Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone antibiotic. It Inhibits bacterial DNA synthesis by inhibiting the activity of bacterial DNA topoisomerase II and IV.
T1293 Gatifloxacin BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155 Topoisomerase , Antibacterial , Antibiotic
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
T13231L Trovafloxacin mesylate Others , DNA/RNA Synthesis , Topoisomerase , Antibacterial
Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the activity of DNA gyrase and topoisomerase IV, enzymes involved in DNA replication. It also acts as an effective and specific inhibitor of the ...
T0331 Moxifloxacin hydrochloride BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl Topoisomerase , Antibacterial , Antibiotic
Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as well as atypical pathogens. Moxifloxacin has been linked to mild ALT elevations ...
T1451 Levofloxacin hydrate Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate DNA gyrase , Topoisomerase , Antibacterial , Antibiotic
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial c...
T16703 Quarfloxin CX-3543 DNA/RNA Synthesis
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...
T1625 Lomefloxacin hydrochloride Lomefloxacin HCl,Okacyn,Maxaquin Topoisomerase , Antibacterial , Antibiotic
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during...
T8747 Levofloxacin hydrochloride DNA gyrase , Topoisomerase
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh...
T31031 CP 74667 UNII-D66A707X1B,CP74667,CP-74667
CP 74667 is a new fluoroquinolone that has good activity against several gram-positive and gram-negative pathogens.
T22797 Gatifloxacin mesylate Others
Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family. It also inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
T36031 Desmethyl Ofloxacin (hydrochloride)
Desmethyl ofloxacin is a metabolite of the fluoroquinolone antibiotic ofloxacin .1 1.Sudo, K., Okazaki, O., Tsumura, M., et al.Isolation and identification of metabolites of ofloxacin in rats, dogs and monkeysXenobiotica...
T23622 Acorafloxacin HCl JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl
Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia.
T22265 Balofloxacin Dihydrate Neuroquinoron Others
Balofloxacin is a fluoroquinolone antibiotic with oral activity.
T10420 Avarofloxacin JNJ-Q2 Others
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
T30684 Cadrofloxacin CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940
Cadrofloxacin (Caderofloxacin, CS-940) is a novel fluoroquinolone antimicrobial agent.
T13346 WQ3810 KPI-10 free base Others
WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.
T81412 Pradofloxacin
Pradofloxacin is a third-generation fluoroquinolone antibacterial agent.
T3522 Tosufloxacin tosilate Others
Tosufloxacin tosilate is a fluoroquinolone antibiotic.
T26368 Tosufloxacin tosylate Tosufloxacin,T-3262,T3262,T 3262
Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections.
T25461 Grepafloxacin, (S)- L-Grepafloxacin
Grepafloxacin, (S)- is an oral broad-spectrum fluoroquinolone antibacterial used for the treatment of bacterial infections.
T31996 Grepafloxacin Hydrochloride DSSTox_CID_26692,OPC-17116,DSSTox_RID_81826,DSSTox_GSID_46692
Grepafloxacin Hydrochloride is an antimicrobial agent, oral broad-spectrum fluoroquinolone. It is used to treat bacterial infections.
T36993 Moxifloxacin N-Sulfate (sodium salt)
Moxifloxacin N-sulfate is a metabolite of moxifloxacin . Moxifloxacin is a fluoroquinolone antibiotic. Formulations containing moxifloxacin have been used in the treatment of bacterial infections, including sinusitis, ch...
T27818 Levonadifloxacin Arginine Salt WCK 771,WCK-771A,WCK 771A,WCK-771,WCK771A,WCK771
Levonadifloxacin, a broad-spectrum fluoroquinolone antibiotic, is used potentially for the treatment of staphylococci.
T26449 A 80556 A-80556,A80556
A 80556, a fluoroquinolone antibiotic, has potent antibacterial activity against gram-positive, gram-negative, and anaerobic organisms.
T26638 Antofloxacin Hydrochloride (S)-Antofloxacin hydrochloride,Antofloxacin HCl
Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis.
T71982 Ofloxacin HCl
Ofloxacin HCl is a synthetic fluoroquinolone ( FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
T33899 PD 131628 PD131628,PD-131628
PD 131628 is a novel fluoroquinolone that is a bioactive form of PD 131112 or CI-990 for use against anaerobic bacteria.

Compounds

Balofloxacin
T0116
Synonym:
Target: DNA gyrase, Antibacterial, Antibiotic
Marbofloxacin
T3117
Synonym: Marbofloxacine,Zeniquin,Marbocyl
Target: Topoisomerase, Antibacterial, Antibiotic
Merafloxacin
T9066
Synonym: CI 934
Target: SARS-CoV
Sitafloxacin Hydrate
T6349
Synonym: DU-6859a,DU6859a hydrate
Target: Antibacterial, Antibiotic
Danofloxacin
T7865
Synonym: Danofloxacino,Danofloxacin free base,Danofloxacine
Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic
Besifloxacin Hydrochloride
T6406
Synonym: BOL-303224-A,Besivance hydrochloride,Besifloxacin HCl
Target: Antibacterial, Antibiotic
Sparfloxacin
T1095
Synonym: AT-4140,PD 131501,Zagam,CI-978
Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic
Gemifloxacin mesylate
T1492
Synonym: LB-20304a,SB-265805S,Gemifloxacin mesylate
Target: DNA gyrase, Topoisomerase, Antibacterial
Pazufloxacin Mesylate
T1620
Synonym: Pazucross,Pazufloxacin mesilate,T-3762,Pazufloxacin methanesulfonate
Target: Topoisomerase, Antibacterial, Antibiotic
Difloxacin hydrochloride
T8142
Synonym: Difloxacin HCl
Target: Antibacterial, Antibiotic
Orbifloxacin
T0292
Synonym: CP-104354
Target: Antibacterial, Antibiotic
Rufloxacin hydrochloride
TQ0221
Synonym: MF-934 hydrochloride
Target: Antibacterial
Fleroxacin
T1294
Synonym: AM-833,RO 23-6240
Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic
Ciprofloxacin
T1640
Synonym: Ciproxan,Ciprobay,Bay o 9867,Bay-09867
Target: Topoisomerase, Antibacterial, Antibiotic
Lomefloxacin
T1444
Synonym: SC47111A
Target: Topoisomerase, Antibacterial, Antibiotic
Pefloxacin Mesylate
T0425
Synonym: Pefloxacinium mesylate
Target: Topoisomerase, Antibacterial, Antibiotic
Delafloxacin meglumine
T8173
Synonym: ABT492 meglumine,WQ-3034 meglumine,RX-3341 meglumine
Target: Antibacterial, Antibiotic
Ibafloxacine
T12649
Synonym: S25930,Ibafloxacin,R835
Target: Antifungal
Delafloxacin
T4063
Synonym: ABT492,WQ-3034,RX-3341
Target: Antibacterial, Antibiotic
Tosufloxacin hydrochloride
T8835
Synonym: A-61827 hydrochloride,T-3262 hydrochloride
Target: Antibacterial
Ofloxacin
T0902
Synonym: DL8280,Hoe-280,Floxin,Tarivid,Oxaldin
Target: Topoisomerase, Antibacterial, Antibiotic
Clinafloxacin
T1283
Synonym: PD 127391,CI-960,AM-1091
Target: Antibacterial, Antibiotic
Moxifloxacin
T0331L
Synonym: Avelox,Moxeza
Target: Others, Antibacterial, Antibiotic
Prulifloxacin
T5394
Synonym: AF 3012,Pruvel,NM441
Target: Topoisomerase, Antibacterial, Antibiotic
Gatifloxacin
T1293
Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155
Target: Topoisomerase, Antibacterial, Antibiotic
Trovafloxacin mesylate
T13231L
Synonym:
Target: Others, DNA/RNA Synthesis, Topoisomerase, Antibacterial
Moxifloxacin hydrochloride
T0331
Synonym: BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl
Target: Topoisomerase, Antibacterial, Antibiotic
Levofloxacin hydrate
T1451
Synonym: Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate
Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic
Quarfloxin
T16703
Synonym: CX-3543
Target: DNA/RNA Synthesis
Lomefloxacin hydrochloride
T1625
Synonym: Lomefloxacin HCl,Okacyn,Maxaquin
Target: Topoisomerase, Antibacterial, Antibiotic
Levofloxacin hydrochloride
T8747
Synonym:
Target: DNA gyrase, Topoisomerase
CP 74667
T31031
Synonym: UNII-D66A707X1B,CP74667,CP-74667
Target:
Gatifloxacin mesylate
T22797
Synonym:
Target: Others
Desmethyl Ofloxacin (hydrochloride)
T36031
Synonym:
Target:
Acorafloxacin HCl
T23622
Synonym: JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl
Target:
Balofloxacin Dihydrate
T22265
Synonym: Neuroquinoron
Target: Others
Avarofloxacin
T10420
Synonym: JNJ-Q2
Target: Others
Cadrofloxacin
T30684
Synonym: CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940
Target:
WQ3810
T13346
Synonym: KPI-10 free base
Target: Others
Pradofloxacin
T81412
Synonym:
Target:
Tosufloxacin tosilate
T3522
Synonym:
Target: Others
Tosufloxacin tosylate
T26368
Synonym: Tosufloxacin,T-3262,T3262,T 3262
Target:
Grepafloxacin, (S)-
T25461
Synonym: L-Grepafloxacin
Target:
Grepafloxacin Hydrochloride
T31996
Synonym: DSSTox_CID_26692,OPC-17116,DSSTox_RID_81826,DSSTox_GSID_46692
Target:
Moxifloxacin N-Sulfate (sodium salt)
T36993
Synonym:
Target:
Levonadifloxacin Arginine Salt
T27818
Synonym: WCK 771,WCK-771A,WCK 771A,WCK-771,WCK771A,WCK771
Target:
A 80556
T26449
Synonym: A-80556,A80556
Target:
Antofloxacin Hydrochloride
T26638
Synonym: (S)-Antofloxacin hydrochloride,Antofloxacin HCl
Target:
Ofloxacin HCl
T71982
Synonym:
Target:
PD 131628
T33899
Synonym: PD131628,PD-131628
Target:
1 2
Cat No. Product Name Synonyms Targets
T6567 Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin Topoisomerase , Antibacterial , Antibiotic
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
T8130 Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan Antibacterial , Antibiotic
Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic,is an antibiotic used to treat a number of bacterial infections
T8046 Tosufloxacin tosylate hydrate Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,T-3262 Tosylate Hydrate Others , Antibacterial , Antibiotic
Tosufloxacin tosylate hydrate (A-61827 tosylate hydrate) is a fluoroquinolone antibacterial agent that is used to treat susceptible infections.
T1276 Danofloxacin mesylate CP 76136-27 DNA/RNA Synthesis , Antibacterial , Antibiotic
Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.
T8384 Gatifloxacin hydrochloride AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride) Topoisomerase , Antibacterial , Antibiotic
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.

Natural Products

Levofloxacin
T6567
Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin
Target: Topoisomerase, Antibacterial, Antibiotic
Ciprofloxacin hydrochloride monohydrate
T8130
Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan
Target: Antibacterial, Antibiotic
Tosufloxacin tosylate hydrate
T8046
Synonym: Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,T-3262 Tosylate Hydrate
Target: Others, Antibacterial, Antibiotic
Danofloxacin mesylate
T1276
Synonym: CP 76136-27
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Gatifloxacin hydrochloride
T8384
Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)
Target: Topoisomerase, Antibacterial, Antibiotic

Recombinant Proteins

Species：
Klebsiella pneumoniae (1)
Mycobacterium smegmatis (1)
Expression System：
E. coli (2)
Tag：
N-terminal 10xHis-tagged (1)
N-terminal 6xHis-tagged (1)
Cat No. Product Name Species Expression System
TMPH-02373 Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) Klebsiella pneumoniae E. coli
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol...
TMPH-02998 Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His) Mycobacterium smegmatis E. coli
The major porin in this organism, forms a water-filled channel which favors the permeation of cations, amino acids, iron Fe(3+) and less efficiently phosphate. Does not transport Fe-ExoMS, the predominant siderophore. Pl...
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