e26

TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.

SK48-E26 is a recombinant protein/biologic targeting IL-1β and can be used for immunology research.

Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.

BE2647 is a selective inhibitor of the mitochondrial pyruvate carrier (MPC), with an EC50 of 70 nM. It exhibits good metabolic stability in mouse liver microsomes. BE2647 can be utilized in research related to metabolic diseases, metabolic-associated steatotic liver disease (MASLD), or metabolic-associated steatohepatitis (MASH).

Kobe2601 is a water-soluble structural analog of Kobe0065. Kobe2601 inhibits Ras-Raf binding. Kobe2601 can be used as a chemical probe to study the inhibitory mechanisms of Ras family proteins.

E260 (Fer and FerT inhibitor) is a Fer/FerT kinase inhibitor

PNU-145156E (FCE26644) a novel angiogenesis inhibitor, has been shown to block circulating angiogenesis promoting growth factor in animal studies and has shown anti-tumor effects in solid tumors in mice.

Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.

Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson's disease, restless leg syndrome and epilepsy.

Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.

Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.

Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.

9-Humulene-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T123654.

Vancide 26 is a bioactive chemical.

MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabolite of Selexipag (S253150).

3-(1-Oxo-4-(prop-2-yn-1-ylamino)isoindolin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64731.

3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64758.

3-(4-Amino-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64797.

3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64810.

3-((4-(Piperazin-1-yl)phenyl)amino)piperidine-2,6-dione hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64817.

4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diamine is a useful organic compound for research related to life sciences. The catalog number is T64884 and the CAS number is 104617-49-4.

8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T65626 and the CAS number is 93703-24-3.

N2-(4-Fluorobenzyl)-5-nitropyridine-2,6-diamine is a useful organic compound for research related to life sciences. The catalog number is T66264 and the CAS number is 33400-49-6.

8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66320 and the CAS number is 853029-57-9.