d glucose

D-Glucose (Glucopyranose) is a monosaccharide, a natural glucose, a sweetener. D-Glucose is the main functional substance of living organisms, and is used as a nutrient in medicine, with diuretic, detoxification and cardiotonic effects.

D-Glucose 6-phosphate (G6P) is glucose that hydroxyl group on carbon 6 is phosphorylated by hexose kinase and is involved in glycolysis, gluconeogenesis, and the pentose phosphate pathway, as well as being converted to glycogen or starch storage. G6P serves as a substrate for glucose 6-phosphatase in the liver and hexose 6-phosphate dehydrogenase (H6PDH) in the lumen of the endoplasmic reticulum.

In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone, and is found in various natural sources, including fungi, algae, and shellfish.

Azido-PEG4-beta-D-glucose is a polyethylene glycol (PEG)-based linker compound crucial for the efficient synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG4-tetra-Ac-beta-D-glucose is a polyethylene glycol (PEG)-based PROTAC linker used for PROTAC synthesis[1].

Propargyl-PEG4-beta-D-glucose is a polyethylene glycol (PEG) derivatized PROTAC linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Propargyl-PEG4-tetra-Ac-beta-D-glucose, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs [1].

Propargyl-PEG2-beta-D-glucose, a polyethylene glycol (PEG) derived linker compound, is specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT serves as a drug-linker conjugate for ADC (antibody-drug conjugate) synthesis.

2-Deoxy-D-glucose 6-phosphate sodium is a derivative of 2-Deoxy-D-glucose, produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis through its effect on hexokinase.

α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabolism by glucose 1,6-bisphosphate in extrahepatic tissues; comparison with fructose 2,6-bisphosphateInt. J. Biochem.22(6)553-557(1990) 2.Maliekal, P., Sokolova, T., Vertommen, D., et al.Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the α-D-phosphohexomutase familyJ. Biol. Chem.282(44)31844-31851(2007) 3.Moustafa, H.M.A., Zaghloul, T.I., and Zhang, Y.-H.P.A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritimaAnal. Biochem.50175-81(2016) 4.Panosian, T.D., Nannemann, D.P., Watkins, G.R., et al.Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycleJ. Biol. Chem.286(10)8043-8054(2011)

2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity.1It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24 mM.

2-deoxy-D-Glucose-13C is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose (T6742) is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.

1-thio-β-D-Glucose tetraacetate is a building block.1,2It has been used in the synthesis of aromatic glucosinolates with anti-inflammatory activity, as well as glucosylated poly(pentafluorostyrene) derivatives for coating magnetic iron oxide nanoparticles. 1.Vo, Q.V., Trenerry, C., Rochfort, S., et al.Synthesis and anti-inflammatory activity of aromatic glucosinolatesBioorg. Med. Chem.21(19)5945-5954(2013) 2.Babiuch, K., Wyrwa, R., Wagner, K., et al.Functionalized, biocompatible coating for superparamagnetic nanoparticles by controlled polymerization of a thioglycosidic monomerBiomacromolecules12(3)681-691(2011)

1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including click chemistry and polymerization. 1-thio-β-D-Glucose can be labeled with technetium-99m for analytical and diagnostic procedures. It can also be used as a substrate for glucose oxidase, which leads to the production of 1-thio-β-D-gluconic acid.

UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolic processes, serving as a precursor and substrate for enzymes in the synthesis of glycogen and sucrose.

UDP-β-D-Glucose is the stereoisomer of UDP-α-D-glucose (sodium salt) . The activities of the UDP-β-D-glucose isomer are not known.

Limocitrin 3-β-D-glucose (BRN: 6394886) is a flavonoid glycoside belonging to the class of organic compounds known as phenolic esters. It is used to make other chemical substances and has been identified in [swamp wallaby apple] and [water primrose].

In cells, D-Glucose 6-phosphate potassium salt (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

2-Deoxy-D-glucose 6-phosphate disodium is a glucose analog that inhibits glycolysis and inhibits the function of hexokinase and glucose-6-phosphate isomerase.

Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (compound 1), a flavonoid glycoside, is found in Euonymus fortunei.

1,2,6-Tri-O-galloyl-β-D-glucose, a chemical compound, can be extracted from Sanguisorba officinalis [1].

Compound 89-5, known as Boc-Lys-PEG8-N-bis(D-glucose), is a drug linker employed in the production of antibody-drug conjugates (ADCs)[1].