chelator

Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.

Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.

L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.

BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.

Chelator 1a has antifungal activity, inhibiting Aspergillus and Candida, and can be used to study fungal infections and cancer.

Deferoxamine (Desferrioxamine B) is an iron chelator. Deferoxamine can be used to reduce the accumulation and deposition of iron in tissues. Deferoxamine can improve neurological dysfunction by inhibiting ferroptosis and neuroinflammation after traumatic brain injury. It has antioxidant, anti-proliferation and anti-tumor activities, and can induce the production of HIF-1α, apoptosis and autophagy in cancer cells. It can be used to treat acute iron toxicity and COVID-19 related diseases.

Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.

Macropa-NH2 is a bifunctional analog of macropa, a carrier molecule that is often coupled to antibodies and is often used as a chelator in cancer research.

Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.

HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.

Norathiol (N-methyl-N-dithiocarboxyglucamine) is an antidote for cadmium poisoning and a metal chelator that promotes the excretion of 109Cd and can be used in the treatment of cadmium poisoning.

MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) is a metal chelator that promotes biliary excretion of Cd.

Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator.

Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.

Nitrilotriacetic acid (Nitriloacetate) is a chelator that tracks and enriches His-tagged proteins in living cells by reacting with divalent metal ions-mediated 6His tagging.

Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.

ADA (N-(2-Acetamido)-2-Iminodiacetic acid) is a biological buffer which can serve as a chelator[1][2].

Succimer (Dimercaptosuccinic acid) is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.

D-(-)-Quinic acid (Kinic acid) is a cellular metal ion chelator, capable of promoting reactions with metal M(II,III) ions under pH-specific conditions. It may possess potent inhibition against alpha-mannosidase and alpha-fucosidase.

Neocuproine is a copper(I) chelator that enhances the purinergic component of vasoconstriction induced by electric field stimulation, and is often used as a ligand reagent and copper ion detector.Neocuproine forms stable complexes with copper ions and can play a catalytic role in certain chemical reactions and analytical methods.Neocuproine acts as a redox-active on the iron and cobalt ligand platform for protection against oxidative damage in NSC34 cells.

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a nontoxic inhibitor of CMV replication, as well as a useful antidote in cases of acute cadmium intoxication.

Phytic acid sodium salt (Sodium phytate hydrate) is known to function as a [PO4]3- storage depot and a precursor for other inositol phosphates and pyrophosphates. It is a potent chelator of divalent and trivalent cations in vitro.

o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene mutation and morphological transformation.