chelator

Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

Chelator 1a has antifungal activity, inhibiting Aspergillus and Candida, and can be used to study fungal infections and cancer.

Deferoxamine(Desferrioxamine B) is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may improve neurological dysfunction by inhibiting ferroptosis and neuroinflammation following traumatic brain injury.Desferrioxamin-B has antioxidant, antiproliferative, Deferoxamine has antioxidant, antiproliferative, and antitumor activities, and can induce HIF-1α production, apoptosis and autophagy in cancer cells.Desferrioxamin-B can be used in the treatment of acute iron toxicity and COVID-19 related diseases.

Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.

Norathiol (N-methyl-N-dithiocarboxyglucamine) is an antidote for cadmium poisoning and a metal chelator that promotes the excretion of 109Cd and can be used in the treatment of cadmium poisoning.

MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) is a metal chelator that promotes biliary excretion of Cd.

HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.

Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.

Macropa-NH2 is a bifunctional analog of macropa, a carrier molecule that is often coupled to antibodies and is often used as a chelator in cancer research.

o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene mutation and morphological transformation.

Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.

Quinaldic acid is an endogenous metabolite.Quinaldic acid is a metal chelator.

BIS-TRIS propane (BTP), a novel multidentate ligand of nickel- and cobalt-based spin clusters, is a metal chelator. BIS-TRIS propane is often used as a zwitterionic buffer for PCR and protein crystallization studies.

EDTA, Disodium Salt, Dihydrate (Ethylenediaminetetraacetic acid disodium dihydrate) is a metal ion chelator used as a protease inhibitor.EDTA, Disodium Salt, Dihydrate is a molecule that is ineffective against cellulase activity and is widely used in protein purification.EDTA, Disodium Salt, Dihydrate promotes the excretion of cellulase by binding to the metals and promotes their excretion.

Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.

EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory and antioxidant activity, slows down damage caused by metal ions, maintains osmotic pressure during protein purification, and can be used in the study of neurological disorders.

ADA (N-(2-Acetamido)-2-Iminodiacetic acid) is a biological buffer which can serve as a chelator[1][2].

Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.

Nitrilotriacetic acid (Nitriloacetate) is a chelator that tracks and enriches His-tagged proteins in living cells by reacting with divalent metal ions-mediated 6His tagging.

Phytic acid sodium salt (Sodium phytate hydrate) is known to function as a [PO4]3- storage depot and a precursor for other inositol phosphates and pyrophosphates. It is a potent chelator of divalent and trivalent cations in vitro.

Neocuproine is a copper(I) chelator that enhances the purinergic component of vasoconstriction induced by electric field stimulation, and is often used as a ligand reagent and copper ion detector.Neocuproine forms stable complexes with copper ions and can play a catalytic role in certain chemical reactions and analytical methods.Neocuproine acts as a redox-active on the iron and cobalt ligand platform for protection against oxidative damage in NSC34 cells.

D-(-)-Quinic acid (Kinic acid) is a cellular metal ion chelator, capable of promoting reactions with metal M(II,III) ions under pH-specific conditions. It may possess potent inhibition against alpha-mannosidase and alpha-fucosidase.

BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.

Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator.