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Results for "

anti-secretory

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    17
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
  • Natural Products
    5
    TargetMol | Natural_Products
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
Pantoprazole Sodium Hydrate
SKF96022 sodium hydrate, SKF96022 (sodium hydrate), BY1023 (sodium hydrate)
T0161164579-32-2
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
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Pasireotide Acetate
TP2207396091-76-2
Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively.
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BTM-1086
T1000872293-17-5In house
BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.
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3-6 months
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Pantoprazole
SKF96022, BY1023
T6928102625-70-7
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
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Pantoprazole sodium
Pantecta, SKF96022 sodium, SKF96022 (sodium), BY1023 (sodium), BY-1023 sodium, Pantoloc
T6929138786-67-1
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+ K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
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Varespladib
LY315920
T2044172732-68-2
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusive crisis, and acute coronary syndrome.
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SCH28080
T1686576081-98-6
SCH28080 is a reversible and K+-competitive inhibitor of gastric H+ K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, anti-secretory and cytoprotective activity.
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6-8 weeks
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Tris(2,4-di-tert-butylphenyl)phosphate
TDTBPP
T1320695906-11-9
Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) isolated from Vitex negundoL inhibits secretory phospholipase A2 (sPLA2). Tris(2,4-di-tert-butylphenyl)phosphate has anti-inflammatory activity.
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Diallylmelamine
N2,N2-Diallylmelamine, N,N-Diallylmelamine, 2,4-Diamino-6-diallylamino-1,3,5-triazine
T20228791-77-0
Diallylmelamine is an anti-secretory agent for the stomach.
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Ro 23-9358
T204941153125-17-8
Ro 23-9358 is a potent inhibitor of secretory phospholipase A2, exhibiting anti-inflammatory properties.
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10-14 weeks
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hexocyclium metilsulfate
Traline, AB-803, AB803, AB 803
T27539115-63-9
Hexocyclium metilsulfate has anti-gastric secretory effects in humans.
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6-8 weeks
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FIZZ-1 (32-51) (mouse)
T76320
FIZZ-1 (32-51) (mouse), a cysteine-rich secretory protein, is primarily expressed in macrophages, bronchial epithelial, and type II alveolar epithelial cells (AEC) during allergic airway inflammation. It also demonstrates an anti-apoptotic effect on lung fibroblasts, suggesting its potential utility in allergic pneumonia research [1] [2].
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ESAT6 Epitope
T89437183273-40-7
ESAT6 Epitope is a known CD4+ T cell epitope within the Early Secretory Antigenic Target 6 (ESAT6), demonstrating nanoscale affinity (IC50=180 nM) for Major Histocompatibility Complex MHC class I. Additionally, ESAT6 Epitope can enhance the anti-tuberculosis cellular immunity initiated by the Bacille Calmette-Guérin vaccine.
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Dehydroabietic acid
Dehydroabietate
TCS17721740-19-8
1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models.
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Rhamnetin
beta-Rhamnocitrin
TN141990-19-7
Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.
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Nimbin
TN46595945-86-8
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect
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(-)-Variabilin
TN5221370102-93-5
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro and shows anti-inflammatory activity after topical or p.o. administration to mice.
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