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Search Result

Search Results for " angina "

Targets

Calcium Channel

49

Compounds

3

Natural Products

Cat No. Product Name Synonyms Targets
T21454 Nicardipine Cardene,Dagan,Antagonil,Flusemide Calcium Channel
Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
T0075 Nicorandil SG-75 Potassium Channel
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b...
T6551 Isosorbide Devicoran,Isobide,Hydronol,Dianhydro-D-glucitol,D-Isosorbide Others
Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
T0342 Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate) VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T1215 Nicardipine hydrochloride RS-69216,Nicardipine HCl,YC-93 Hydrochloride Calcium Channel , Adrenergic Receptor , AChR , Autophagy
Nicardipine hydrochloride (YC-93 Hydrochloride) is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks cal...
T20656 Verapamil NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil P450 , Calcium Channel , P-gp
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias...
T1010 Verapamil hydrochloride Manidon,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride P450 , Calcium Channel , P-gp
Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.
T13154 Tiapamil hydrochloride Ro 11-1781 hydrochloride,ORE 5002 hydrochloride Calcium Channel
Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity and may be used in the study of angina and cardiovascular disease.
T11148 Ecastolol Adrenergic Receptor
Ecastolol has anti-angina activity and is an adrenergic receptor antagonist.
T34648 Sinitrodil ITF296,ITF-296,ITF 296 Guanylate cyclase
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
T1479 Isosorbide dinitrate Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate Others , NO Synthase
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.
T35161 Xemilofiban SC-54684A,SC54684A,SC 54684A Others
Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina.
T8143 Bevantolol hydrochloride NC-1400 hydrochloride Calcium Channel , Adrenergic Receptor
Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
T68060 Elgodipine
Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression ...
T27808 Lefradafiban BIBU 104,BIBU104,BIBU-104 Others
Lefradafiban（BIBU-104） is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.
T1282 Carteolol hydrochloride Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan Adrenergic Receptor
Carteolol hydrochloride (Abbott-43326) is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 receptors with no membrane-s...
T68073 Flosatidil Calcium Channel
Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases, and can be used in the study of angina pectoris.
T8580 Bupranolol Adrenergic Receptor
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T6633 Ranolazine CVT 303,Ranexa,RS 43285-003 Calcium Channel , Sodium Channel
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the...
T30586L Brefonalol HCl Brefonalol HCl(103880-26-8 Free base) Adrenergic Receptor
Brefonalol HCl is an ADRA antagonist used in the treatment of neurological disorders and cardiovascular diseases and can be used in the study of angina pectoris, arrhythmias and hypertension.
T0988 Trimetazidine dihydrochloride Yoshimilon,Kyurinett,Vastarel F Autophagy , Fatty Acid Synthase
Trimetazidine dihydrochloride (Vastarel F) can improve myocardial glucose utilization by inhibiting fatty acid metabolism. Trimetazidine is the first cytoprotective anti-ischemic agent, also used as a vasodilator in isch...
T0230 Prasugrel LY640315,CS-747,PCR 4099 P2Y Receptor
Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those...
T50077 M-Nisoldipine 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Others
m-Nisoldipine (3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) is a dihydropyridine calcium channel blocker, a derivative of nisoldipine, that blocks L-type calcium chann...
T24873 TGX-115 TGX 115 PI3K
TGX-115 is a cell-permeable and potent inhibitor of the PI 3-K isoform p110β/p110δ (IC50 values of 0.13 μM for p110β and 0.63 μM for p110δ), an enzyme that regulates platelet adhesion and inhibits phosphoinositide (PI) 3...
T36665 Dehydro Nifedipine BAY-b 4759
Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used i...
T31206 Darexaban YM 150,Darexaban, Tanexaban,YM150 Factor Xa
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...
T28191 NP-252 NP252
NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.
T69494 Toliprolol
Toliprolol is an adrenergic receptor antagonist with some stimulant action; it has been proposed for angina pectoris.
T8663L Nifenalol
Nifenalol is an adrenergic beta-blocker with good antiarrhythmic properties. It tends to lower blood pressure and provide protection against angina.
T28800 SL-870495 SL870495
SL-870495, a calcium channel antagonist, is used potentially for the treatment of angina pectoris.
T27197 Dopropidil hydrochloride ORG-30701,CERM-4205,CERM4205,ORG30701
Dopropidil, a calcium channel antagonist, is used potentially for the treatment of arrhymia and angina pectoris.
T24659 Prenylamine lactate Agozol,Angormin
Prenylamine lactate is a drug formerly used in the treatment of angina pectoris. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity.
T71583 Amlodipine hydrochloride, (R)-
Amlodipine hydrochloride, (R)-, is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vess...
T10229 Acebutolol D7 Others
Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.
T25575 KF 14124 KF14124,Dptpp-2-ismn,KF-14124
KF 14124 exhibits potent anti-ischemic activity in a lysine-vasopressin-induced angina pectoris model (rats).
T12358 Palonidipine Calcium Channel
Palonidipine is an antagonist of calcium, is potential for the therapy of angina-pectoris and hypertension.
T28457 Proxodolol hydrochloride
Proxodolol, a β-adrenergic receptor antagonist, is used potentially for the treatment of glaucoma, hypertension and angina.
T68213 Palonidipine HCl
Palonidipine HCl is a calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.
T33673 Niludipine Niludipina,BAY-a 7168,Bay a 7168,Niludipinum
Nirudipine is a double (2-propoxyethyl) analogist of nifedipine and a calcium channel blocker, which is also a safe anti-angina Ca2+ antagonist with a broad range of efficacy for all types of angina. At the same time, Ni...
T61138 Bevantolol
Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].
T21010 Diacetolol Acetylacebutolol,(+-)-Diacetolol,M and B 16942
Diacetolol is the major metabolite of acebutolol, a selective beta blockers used to treat hypertension, angina pectoris and arrhythmia.
T11080 Dopropidil Calcium Channel
Dopropidil is a new anti-angina pectoris calcium regulator, which has intracellular calcium antagonist activity and anti-ischemic effects in various predicted animal models.
T68367 Amlodipine orotate
Amlodipine orotate is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers ...
T32770 Linsidomine CV 664
Lincydomine is a smooth muscle relaxant, beneficial to the treatment of unstable angina pectoris, but also can open the respiratory tract of humans and guinea pigs.
T24631 Pheniprazine hydrochloride Pheniprazine HCl,NSC 17766,CCRIS 1417,NSC-17766,NSC17766
Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor of the hydrazine chemical class. It was also used in the treatment of angina pectoris and schizophrenia.
T24863 Tedisamil Tedisamilum,Pulzium
Tedisamil is a blocker of K+ currents in cardiac tissues, exerts bradycardic effects. It is an antiarrhythmic drug with predominantly class III activity. It has shown clinical efficacy in angina pectoris.
T0112L Diltiazem Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401
Diltiazem is a non-dihydropyridine (non-DHP) calcium channel blocker that relaxes the smooth muscle in arterial walls, thus opening (dilating) arteries, allowing easier blood flow, and lowering blood pressure, and is use...
T62909 SGC agonist 2
SGC agonist 2 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 2 has potential for cardiovascular disease (heart failure, angina, pulmonary hypertension, myocardial infarction) and fibrotic disease (renal...
T71402 Nicorandil-d4
Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir...

Compounds

Nicardipine
T21454
Synonym: Cardene,Dagan,Antagonil,Flusemide
Target: Calcium Channel
Nicorandil
T0075
Synonym: SG-75
Target: Potassium Channel
Isosorbide
T6551
Synonym: Devicoran,Isobide,Hydronol,Dianhydro-D-glucitol,D-Isosorbide
Target: Others
Carvedilol phosphate hemihydrate
T0342
Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)
Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy
Nicardipine hydrochloride
T1215
Synonym: RS-69216,Nicardipine HCl,YC-93 Hydrochloride
Target: Calcium Channel, Adrenergic Receptor, AChR, Autophagy
Verapamil
T20656
Synonym: NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil
Target: P450, Calcium Channel, P-gp
Verapamil hydrochloride
T1010
Synonym: Manidon,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride
Target: P450, Calcium Channel, P-gp
Tiapamil hydrochloride
T13154
Synonym: Ro 11-1781 hydrochloride,ORE 5002 hydrochloride
Target: Calcium Channel
Ecastolol
T11148
Synonym:
Target: Adrenergic Receptor
Sinitrodil
T34648
Synonym: ITF296,ITF-296,ITF 296
Target: Guanylate cyclase
Isosorbide dinitrate
T1479
Synonym: Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate
Target: Others, NO Synthase
Xemilofiban
T35161
Synonym: SC-54684A,SC54684A,SC 54684A
Target: Others
Bevantolol hydrochloride
T8143
Synonym: NC-1400 hydrochloride
Target: Calcium Channel, Adrenergic Receptor
Elgodipine
T68060
Synonym:
Target:
Lefradafiban
T27808
Synonym: BIBU 104,BIBU104,BIBU-104
Target: Others
Carteolol hydrochloride
T1282
Synonym: Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan
Target: Adrenergic Receptor
Flosatidil
T68073
Synonym:
Target: Calcium Channel
Bupranolol
T8580
Synonym:
Target: Adrenergic Receptor
Ranolazine
T6633
Synonym: CVT 303,Ranexa,RS 43285-003
Target: Calcium Channel, Sodium Channel
Brefonalol HCl
T30586L
Synonym: Brefonalol HCl(103880-26-8 Free base)
Target: Adrenergic Receptor
Trimetazidine dihydrochloride
T0988
Synonym: Yoshimilon,Kyurinett,Vastarel F
Target: Autophagy, Fatty Acid Synthase
Prasugrel
T0230
Synonym: LY640315,CS-747,PCR 4099
Target: P2Y Receptor
m-Nisoldipine
T50077
Synonym: 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Target: Others
TGX-115
T24873
Synonym: TGX 115
Target: PI3K
Dehydro Nifedipine
T36665
Synonym: BAY-b 4759
Target:
Darexaban
T31206
Synonym: YM 150,Darexaban, Tanexaban,YM150
Target: Factor Xa
NP-252
T28191
Synonym: NP252
Target:
Toliprolol
T69494
Synonym:
Target:
Nifenalol
T8663L
Synonym:
Target:
SL-870495
T28800
Synonym: SL870495
Target:
Dopropidil hydrochloride
T27197
Synonym: ORG-30701,CERM-4205,CERM4205,ORG30701
Target:
Prenylamine lactate
T24659
Synonym: Agozol,Angormin
Target:
Amlodipine hydrochloride, (R)-
T71583
Synonym:
Target:
Acebutolol D7
T10229
Synonym:
Target: Others
KF 14124
T25575
Synonym: KF14124,Dptpp-2-ismn,KF-14124
Target:
Palonidipine
T12358
Synonym:
Target: Calcium Channel
Proxodolol hydrochloride
T28457
Synonym:
Target:
Palonidipine HCl
T68213
Synonym:
Target:
Niludipine
T33673
Synonym: Niludipina,BAY-a 7168,Bay a 7168,Niludipinum
Target:
Bevantolol
T61138
Synonym:
Target:
Diacetolol
T21010
Synonym: Acetylacebutolol,(+-)-Diacetolol,M and B 16942
Target:
Dopropidil
T11080
Synonym:
Target: Calcium Channel
Amlodipine orotate
T68367
Synonym:
Target:
Linsidomine
T32770
Synonym: CV 664
Target:
Pheniprazine hydrochloride
T24631
Synonym: Pheniprazine HCl,NSC 17766,CCRIS 1417,NSC-17766,NSC17766
Target:
Tedisamil
T24863
Synonym: Tedisamilum,Pulzium
Target:
Diltiazem
T0112L
Synonym: Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401
Target:
SGC agonist 2
T62909
Synonym:
Target:
Nicorandil-d4
T71402
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T3S0128 Hydroprotopine Others
Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
TN4323 Isorauhimbine Antibiotic
Isorauhimbine is an alkaloid derived from R. serpentina with anticancer, anti-inflammatory and antimicrobial activities and is used in the treatment of cardiovascular diseases such as hypertension, arrhythmia and angina ...
TN2303 Viscumneoside III Tyrosinase
Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.

Natural Products

Hydroprotopine
T3S0128
Synonym:
Target: Others
Isorauhimbine
TN4323
Synonym:
Target: Antibiotic
Viscumneoside III
TN2303
Synonym:
Target: Tyrosinase
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