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Results for "

Decarboxylase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    80
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    7
    TargetMol | Peptide_Products
  • Natural Products
    20
    TargetMol | Natural_Products
  • Recombinant Protein
    29
    TargetMol | Recombinant_Protein
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    5
    TargetMol | Isotope_Products
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    11
    TargetMol | Antibody_Products
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    TargetMol | Disease_Modeling_Products
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    TargetMol | Inhibitors_Agonists
4-Bromo-3-hydroxybenzoic acid
T745414348-38-0
4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase.
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Mab Aspartate Decarboxylase-IN-1
T606132755712-12-8
Mab Aspartate Decarboxylase-IN-1 is a potent inhibitor of aspartate decarboxylase (PanD) with an IC50 of 56.3 μM and exhibits antibacterial activity [1].
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6-8 weeks
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Tyrosine decarboxylase
T736149002-09-9
Tyrosine decarboxylase (TDC; TyrDC), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the decarboxylation of tyrosine, leading to the production of tyramine and carbon dioxide. This enzyme is prevalent in plants, insects, and various microorganisms, playing a significant role in biochemical research.
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Carbidopa monohydrate
S(-)-Carbidopa, Carbidopa Hydrate
T214838821-49-7
Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.
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Carbidopa
Lodosyn, (S)-(-)-Carbidopa
T679528860-95-9
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
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L-Ornithine
(S)-2,5-Diaminopentanoic acid
T073770-26-8
L-Ornithine ((S)-2,5-Diaminopentanoic acid) exhibits an anti-fatigue function by promoting ammonia excretion and enhancing energy consumption efficiency.
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α-Hydroxyglutaric Acid Lithium
α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base)
T36624L In house
α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synthase and mTOR signaling.
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Eflornithine hydrochloride hydrate
Difluoromethylornithine hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate, Eflornithine hydrochloride, MDL-71782 hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, Eflornithine hydrochloride Monohydrate
T259396020-91-6
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific and irreversible inhibitor of the ornithine decarboxylase (ODC). Eflornithine hydrochloride hydrate has antitumor activity and has also been used in the hirsutism Eflornithine hydrochloride hydrate has antitumor activity and is also used in the treatment of hirsutism.
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Tritoqualine
Hypostamine, Inhibostamin
T1716614504-73-5
Tritoqualine is used as an inhibitor of histidine decarboxylase.
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6-8 weeks
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(Rac)-AMXT-1501 4HCl
T103132771343-93-0In house
(Rac)-AMXT-1501 4HCl is a polyamine transport inhibitor that inhibits polyamine transport and acts synergistically with cisplatin in HNSCC. (Rac)-AMXT-1501 4HCl has potential antimicrobial activity and inhibits neuroblastoma cell proliferation and pneumococcal pod biosynthesis by targeting ornithine decarboxylase and polyamine transport.
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Azaribine
NSC 67239, 2',3',5'-Tri-O-acetyl-6-azauridine
T251302169-64-4In house
Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has been used in the study of Zika virus (ZIKV) infections, and in the study of psoriasis, arthritis and mycosis fungoides. Azaribine is used to study Zika virus (ZIKV) infections, psoriasis and mycosis fungoides.
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7-10 days
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α-(difluoromethyl)-DL-Arginine
α-(difluoromethyl)-DL-Arginine, RMI 71897, DFMA
T3544969955-43-7In house
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, α-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models.
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8-10 weeks
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Sardomozide dihydrochloride
CGP 48664 dihydrochloride, Sardomozide dihydrochloride
T4676138794-73-7In house
Sardomozide dihydrochloride (CGP 48664 dihydrochloride) is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).
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4-Hydroxyphenylacetamide
Fr1414517194-82-0
4-Hydroxyphenylacetamide, HpdBCA decarboxylase inhibitor, is used as a whitening ingredient in cosmetics and skin care products. It can be used in the synthesis of aminoacil.
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7-10 days
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TargetMol | Inhibitor Sale
Methyldopa
MK-351, L-(-)-α-Methyldopa
T0505555-30-6
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.
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L-DOPA
Levodopa, 3,4-Dihydroxyphenylalanine
T084859-92-7
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. It is a prodrug converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. In the brain, levodopa is decarboxylated to dopamine, stimulating dopaminergic receptors and compensating for depleted endogenous dopamine in Parkinson's disease. To ensure adequate concentrations reach the central nervous system, levodopa is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, reducing peripheral decarboxylation and increasing CNS dopamine delivery.
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Benserazide hydrochloride
Serazide, Ro 4-4602, Benserazide HCl
T151714919-77-8
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
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Isotretinoin
13-cis-Retinoic acid
T16114759-48-2
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs), which act as transcription factors that promote cell differentiation and apoptosis. This naturally occurring retinoic acid has potential antineoplastic activity, exhibits immunomodulatory and anti-inflammatory responses, and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.
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L-Allylglycine
T3719016338-48-0
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol g per hour ex vivo in mouse brain preparations. L-Allylglycine (1.2 mmol kg, i.p.) induces convulsions and decreases GABA concentration throughout the cerebellum, pons, medulla, striatum, cortex, and hippocampus in mice. Chronic administration (3.2 μg 0.5 μl per hour for 13 days) of L-allylglycine in rats increases locomotor activity in an open field test and impairs attention in the 5-choice serial reaction time task (5CSRTT). In vitro, L-allylglycine inhibits GAD only when used at high concentrations (1-80 mM). The more potent in vivo activity can be attributed to metabolic conversion of L-allylglycine to 2-keto-4-pentanoic acid, a more potent convulsant and GAD inhibitor.
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Methyl L-histidinate dihydrochloride
L-Histidine methyl ester dihydrochloride
T39377389-87-9
The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production with activty value of 1.8 μM
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Homovanillic acid
Vanillacetic acid, Vanilacetic acid, Homovaniuic acid
T3S0507306-08-1
Homovanillic acid (Vanillacetic acid), a dopamine metabolite, is linked to aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.
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D-Arginine
H-D-Arg-OH
T41330157-06-2
D-Arginine is the D-isomer and inactive form of L-Arginine.D-Arginine is an endogenous metabolite and inhibitor of EC 4.1.1.19 (arginine decarboxylase), has broad-spectrum toxicity to microorganisms, and acts as a regulator of microbial subpopulations.
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7-10 days
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Suberic acid
Octanedioic acid, 1,8-Octanedioic acid
T4734505-48-6
Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid are found in individuals with medium-chain acyl-CoA dehydrogenase deficiency (MCAD). Suberic acid is also associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency.
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Sodium phenylpyruvate
Phenylpyruvic acid, sodium salt
T4891114-76-1
Sodium phenylpyruvate (Phenylpyruvic acid, sodium salt) is a substrate for phenylpyruvate decarboxylase and phenylpyruvate tautomerase.
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