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Syk

Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene.
Cat. No. Product name CAS No. Purity Chemical Structure
T4348 Syk Inhibitor II 726695-51-8 98%
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
T16995 TAS05567 1429038-15-2 98%
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
T11824 Lanraplenib succinate 1800047-00-0 98%
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
T28281 OXSI-2 622387-85-3 98%
OXSI-2 is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated e...
T11824L Lanraplenib monosuccinate 1800046-97-2 98%
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
TN1549 Damnacanthal 477-84-9 98%
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
TN7075 Linocinnamarin 554-87-0 98%
Linocinnamarin is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen-stimulated degranulation by LN is mainly due to inactivation of S...
T0465 Ellagic acid 476-66-4 98%
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
T2487 Cerdulatinib 1198300-79-6 98%
Cerdulatinib is an novel oral dual Syk/JAK inhibitor.
T4391 Syk Inhibitor II dihydrochloride 227449-73-2 98%
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chain...
T14331 Gusacitinib 1425381-60-7 98%
Gusacitinib (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
T6776 BAY 61-3606 dihydrochloride 648903-57-5 98%
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
T3185 R112 575474-82-7 98%
R112 is an ATP-competitive inhibitor of Syk kinase.
T11824LL Lanraplenib 1800046-95-0 98%
Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits S...
T0610 Piceatannol 10083-24-6 98%
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
T2467 R406 free base 841290-80-0 98%
R406 (free base) is a potent Syk inhibitor.
T4209 TAK-659 hydrochloride 1952251-28-3 98%
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent ...
T6104 Cerdulatinib hydrochloride 1369761-01-2 98%
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and S...
T7035 ANTHRAQUINONE-2-CARBOXYLIC ACID 117-78-2 98%
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of frui...
T6101 Entospletinib 1229208-44-9 98%
Entospletinib (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.
Syk Inhibitor II
T4348
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
TAS05567
T16995
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
Lanraplenib succinate
T11824
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
OXSI-2
T28281
OXSI-2 is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated e...
Lanraplenib monosuccinate
T11824L
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
Damnacanthal
TN1549
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
Linocinnamarin
TN7075
Linocinnamarin is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen-stimulated degranulation by LN is mainly due to inactivation of S...
Ellagic acid
T0465
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
Cerdulatinib
T2487
Cerdulatinib is an novel oral dual Syk/JAK inhibitor.
Syk Inhibitor II dihydrochloride
T4391
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chain...
Gusacitinib
T14331
Gusacitinib (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
BAY 61-3606 dihydrochloride
T6776
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
R112
T3185
R112 is an ATP-competitive inhibitor of Syk kinase.
Lanraplenib
T11824LL
Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits S...
Piceatannol
T0610
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
R406 free base
T2467
R406 (free base) is a potent Syk inhibitor.
TAK-659 hydrochloride
T4209
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent ...
Cerdulatinib hydrochloride
T6104
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and S...
ANTHRAQUINONE-2-CARBOXYLIC ACID
T7035
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of frui...
Entospletinib
T6101
Entospletinib (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.
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