T4348 |
Syk Inhibitor II
|
726695-51-8
|
98%
|
|
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
|
T16995 |
TAS05567
|
1429038-15-2
|
98%
|
|
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
|
T11824 |
Lanraplenib succinate
|
1800047-00-0
|
98%
|
|
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
|
T28281 |
OXSI-2
|
622387-85-3
|
98%
|
|
OXSI-2 is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated e...
|
T11824L |
Lanraplenib monosuccinate
|
1800046-97-2
|
98%
|
|
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
|
TN1549 |
Damnacanthal
|
477-84-9
|
98%
|
|
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
|
TN7075 |
Linocinnamarin
|
554-87-0
|
98%
|
|
Linocinnamarin is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen-stimulated degranulation by LN is mainly due to inactivation of S...
|
T0465 |
Ellagic acid
|
476-66-4
|
98%
|
|
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
|
T2487 |
Cerdulatinib
|
1198300-79-6
|
98%
|
|
Cerdulatinib is an novel oral dual Syk/JAK inhibitor.
|
T4391 |
Syk Inhibitor II dihydrochloride
|
227449-73-2
|
98%
|
|
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chain...
|
T14331 |
Gusacitinib
|
1425381-60-7
|
98%
|
|
Gusacitinib (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
|
T6776 |
BAY 61-3606 dihydrochloride
|
648903-57-5
|
98%
|
|
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
|
T3185 |
R112
|
575474-82-7
|
98%
|
|
R112 is an ATP-competitive inhibitor of Syk kinase.
|
T11824LL |
Lanraplenib
|
1800046-95-0
|
98%
|
|
Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits S...
|
T0610 |
Piceatannol
|
10083-24-6
|
98%
|
|
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
|
T2467 |
R406 free base
|
841290-80-0
|
98%
|
|
R406 (free base) is a potent Syk inhibitor.
|
T4209 |
TAK-659 hydrochloride
|
1952251-28-3
|
98%
|
|
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent ...
|
T6104 |
Cerdulatinib hydrochloride
|
1369761-01-2
|
98%
|
|
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and S...
|
T7035 |
ANTHRAQUINONE-2-CARBOXYLIC ACID
|
117-78-2
|
98%
|
|
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of frui...
|
T6101 |
Entospletinib
|
1229208-44-9
|
98%
|
|
Entospletinib (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.
|