Syk

Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene.

Cat. No.	Product name	CAS No.	Purity
T16995	TAS05567	1429038-15-2	98%
T16995	TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
T11824L	Lanraplenib monosuccinate	1800046-97-2	98%
T11824L	Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
T22430	SRX3207	2254693-15-5	98%
T22430	SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.
TN7075	Linocinnamarin	554-87-0	98%
TN7075	Linocinnamarin is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen-stimulated degranulation by LN is mainly due to inactivation of S...
TN1549	Damnacanthal	477-84-9	98%
TN1549	Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
T6003	GSK1904529A	1089283-49-7	98%
T6003	GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
T11824	Lanraplenib succinate	1800047-00-0	98%
T11824	Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
T6104	Cerdulatinib hydrochloride	1369761-01-2	98%
T6104	Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and S...
T16776	RO9021	1446790-62-0	98%
T16776	RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).
T9789	Cevidoplenib dimesylate hydrochloride	269062-93-3	98%
T9789	Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.
T2605	Fostamatinib Disodium	1025687-58-4	96.13%
T2605	Fostamatinib Disodium is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.
T39437	Cevidoplenib dimesylate	2043659-93-2	96.16%
T39437	Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
T6115	Fostamatinib	901119-35-5	98.3%
T6115	Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
T6594	MNS	1485-00-3	98.45%
T6594	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T4263	BAY 61-3606	732983-37-8	98.72%
T4263	BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effec...
T6174	R406	841290-81-1	98.82%
T6174	R406 is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.
T2467	R406 free base	841290-80-0	99.31%
T2467	R406 (free base) is a potent Syk inhibitor.
T6057	URMC-099	1229582-33-5	99.32%
T6057	URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)...
T0610	Piceatannol	10083-24-6	99.39%
T0610	Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
T11824LL	Lanraplenib	1800046-95-0	99.42%
T11824LL	Lanraplenib is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits S...