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Neuropeptide Y Receptor

Neuropeptide Y receptors are a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide hormones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in the control of a diverse set of behavioral processes including appetite, circadian rhythm, and anxiety.
Cat. No. Product name CAS No. Purity Chemical Structure
T12895 SHA 68 847553-89-3 98%
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectivel...
T8456 GALNON 475115-35-6 98%
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
TP1137L Pancreatic Polypeptide (human) acetate 98%
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
TP1140L Neuropeptide Y (29-64), amide, human acetate 98%
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
TP1380 Galanin (1-16), mouse, porcine, rat 125118-77-6 98%
Galanin(1-16),mouse,porcine,rat(TFA) is a Galanin receptor agonist with a Kd value of 3nM..
TP1982L Neuropeptide S (Rat) acetate TP1982L 98%
Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor. Neuropeptide S (Rat) acetate can b...
TP1981L Neuropeptide S (Mouse) acetate TP1981L 98%
Neuropeptide S (Mouse) acetate is a bioactive peptide. Neuropeptide S (Mouse) acetate, as a neurotransmitter/neuromodulator of 20 amino acids, can be used for th...
T14671 BMS-193885 186185-03-5 98%
BMS-193885 is a selective, brain-penetrant, and competitive antagonist of the neuropeptide Y1 receptor with a Ki of 3.3 nM, and an IC50 of 5.9 nM for hY1.
TP1044L Pancreatic Polypeptide, rat acetate 98%
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.
TP1993L M617 acetate 98%
M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content i...
TP1059 Peptide YY (PYY) (3-36), human 126339-09-1 98%
Peptide YY (PYY) (3-36), human is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
TP2206 [Leu31,Pro34]-Neuropeptide Y (porcine) 125580-28-1 98%
High affinity neuropeptide Y Y1 receptor agonist
TP1994L M871 acetate 98%
M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptive ef...
T24121 GW438014A 469861-49-2 98%
GW438014A is a potent and selective NPY-Y5 receptor antagonist.GW438014A inhibits food intake and reduces body weight gain in obese rodents.
T21646L AR-M 1896 Acetate T21646L 98%
AR-M 1896 Acetate is the selective agonist of GalR2.
TP1930L1 Spexin acetate(1370290-58-6 free base) TP1930L1 98%
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galani...
T1997 JNJ-31020028 1094873-14-9 98%
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold ...
TP1937L1 RFRP-1 (human) acetate(311309-25-8 free base) TP1937L1 98%
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile ...
T21611L BWX 46 Acetate T21611L 98%
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
T8963 CYM2503 1308833-36-4 98%
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthos...
SHA 68
T12895
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectivel...
GALNON
T8456
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
Pancreatic Polypeptide (human) acetate
TP1137L
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
Neuropeptide Y (29-64), amide, human acetate
TP1140L
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
Galanin (1-16), mouse, porcine, rat
TP1380
Galanin(1-16),mouse,porcine,rat(TFA) is a Galanin receptor agonist with a Kd value of 3nM..
Neuropeptide S (Rat) acetate
TP1982L
Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor. Neuropeptide S (Rat) acetate can b...
Neuropeptide S (Mouse) acetate
TP1981L
Neuropeptide S (Mouse) acetate is a bioactive peptide. Neuropeptide S (Mouse) acetate, as a neurotransmitter/neuromodulator of 20 amino acids, can be used for th...
BMS-193885
T14671
BMS-193885 is a selective, brain-penetrant, and competitive antagonist of the neuropeptide Y1 receptor with a Ki of 3.3 nM, and an IC50 of 5.9 nM for hY1.
Pancreatic Polypeptide, rat acetate
TP1044L
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.
M617 acetate
TP1993L
M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content i...
Peptide YY (PYY) (3-36), human
TP1059
Peptide YY (PYY) (3-36), human is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
[Leu31,Pro34]-Neuropeptide Y (porcine)
TP2206
High affinity neuropeptide Y Y1 receptor agonist
M871 acetate
TP1994L
M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptive ef...
GW438014A
T24121
GW438014A is a potent and selective NPY-Y5 receptor antagonist.GW438014A inhibits food intake and reduces body weight gain in obese rodents.
AR-M 1896 Acetate
T21646L
AR-M 1896 Acetate is the selective agonist of GalR2.
Spexin acetate(1370290-58-6 free base)
TP1930L1
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galani...
JNJ-31020028
T1997
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold ...
RFRP-1 (human) acetate(311309-25-8 free base)
TP1937L1
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile ...
BWX 46 Acetate
T21611L
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
CYM2503
T8963
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthos...
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