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Neurokinin receptor

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T7559 Neurokinin A(4-10) 97559-35-8
Neurokinin A(4-10)
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
T7631 Eledoisin Related Peptide 2990-43-4
Eledoisin Related Peptide
Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand.
T78104 Fosnetupitant chloride monohydrochloride 1643757-72-5 98%
Fosnetupitant chloride monohydrochloride
Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1 rec...
T78757 NK3R-IN-1 2854331-14-7 98%
NK3R-IN-1
NK3R-IN-1 (compound 16x), an orally active imidazolepiperazine derivative, acts as a Neurokinin Receptor NK3R inhibitor and has been shown to reduce blood lutein...
T80031 [D-Pro2] Spantide I TFA 98%
[D-Pro2] Spantide I TFA
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].
T7396 Substance P(1-7) 68060-49-1 98%
Substance P(1-7)
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammato...
T16406 Orvepitant maleate 579475-24-4 98%
Orvepitant maleate
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant...
T24697 R 396 129809-09-2 98%
R 396
R 396 (Acleu-asp-gln-trp-phe-glynh2) is a linear hexapeptide and is also an NK-2 tachykinin receptor antagonist.
T10892 CS-003 Free base 191672-52-3 98%
CS-003 Free base
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 ...
TP1177 Eledoisin 69-25-0 98%
Eledoisin
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of...
TQ0087 NKP608 177707-12-9 98%
NKP608
NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.
T35344 Maropitant citrate 359875-09-5 98%
Maropitant citrate
Maropitant citrate is a useful organic compound for research related to life sciences. The catalog number is T35344 and the CAS number is 359875-09-5.
T19518 Physalaemin 2507-24-6 98%
Physalaemin
Physalaemin is a non-mammalian tachykinin.
T10688 Casopitant mesylate 414910-30-8 98%
Casopitant mesylate
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of anti...
T16849 SB-222200 174635-69-9 99.97%
SB-222200
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
T6905 Netupitant 290297-26-6 99.95%
Netupitant
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
T8789 N-Acetyl-L-tryptophan 1218-34-4 99.93%
N-Acetyl-L-tryptophan
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
T1743 Aprepitant 170729-80-3 99.9%
Aprepitant
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome...
T13306L Vapreotide acetate 849479-74-9 99.89%
Vapreotide acetate
Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).
TP1572 GR-73632 133156-06-6 99.68%
GR-73632
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).
Neurokinin A(4-10)
T7559
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
Eledoisin Related Peptide
T7631
Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand.
Fosnetupitant chloride monohydrochloride
T78104
Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1 rec...
NK3R-IN-1
T78757
NK3R-IN-1 (compound 16x), an orally active imidazolepiperazine derivative, acts as a Neurokinin Receptor NK3R inhibitor and has been shown to reduce blood lutein...
[D-Pro2] Spantide I TFA
T80031
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].
Substance P(1-7)
T7396
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammato...
Orvepitant maleate
T16406
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant...
R 396
T24697
R 396 (Acleu-asp-gln-trp-phe-glynh2) is a linear hexapeptide and is also an NK-2 tachykinin receptor antagonist.
CS-003 Free base
T10892
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 ...
Eledoisin
TP1177
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of...
NKP608
TQ0087
NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.
Maropitant citrate
T35344
Maropitant citrate is a useful organic compound for research related to life sciences. The catalog number is T35344 and the CAS number is 359875-09-5.
Physalaemin
T19518
Physalaemin is a non-mammalian tachykinin.
Casopitant mesylate
T10688
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of anti...
SB-222200
T16849
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
Netupitant
T6905
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
N-Acetyl-L-tryptophan
T8789
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
Aprepitant
T1743
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome...
Vapreotide acetate
T13306L
Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).
GR-73632
TP1572
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).
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TargetMol