T3289 |
Amifostine
|
20537-88-6
|
98%
|
|
Amifostine anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
|
T9627 |
PHD-1-IN-1
|
2009343-14-8
|
98%
|
|
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).
|
T50099 |
HIF-2α-IN-4
|
882268-69-1
|
98%
|
|
HIF-2a translation inhibitor is a compound used as a molecular building block.
|
T1141 |
Fenbendazole
|
43210-67-9
|
98%
|
|
Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.
|
T7802 |
M1001
|
874590-32-6
|
98%
|
|
M1001 is a HIF-2α agonist.
|
T3S2344 |
β,β-Dimethylacrylshikonin
|
24502-79-2
|
98%
|
|
1. Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combine...
|
T11589 |
Hydroxycitric acid tripotassium hydrate
|
6100-05-6
|
98%
|
|
Potassium citrate monohydrate effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydr...
|
T5176 |
Desidustat
|
1616690-16-4
|
98%
|
|
Desidustat is an inhibitor of HIF hydroxylase.
|
T29797 |
AKB-6899
|
1007377-55-0
|
98%
|
|
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macr...
|
T21653 |
1,4-DPCA
|
331830-20-7
|
98%
|
|
1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HI...
|
T5537 |
IDF-11774
|
1429054-28-3
|
98%
|
|
IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).
|
TL0001 |
Dencichine
|
5302-45-4
|
98%
|
|
Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation ...
|
T5684 |
Ethyl 3,4-dihydroxybenzoate
|
3943-89-3
|
98%
|
|
Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
|
T0256 |
Citric acid trilithium salt tetrahydrate
|
6080-58-6
|
98%
|
|
Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
|
T67831 |
HIF-2α agonist 2
|
2750141-15-0
|
98%
|
|
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structu...
|
T1152 |
Albendazole
|
54965-21-8
|
98%
|
|
Albendazole is used as a drug indicated for the treatment of a variety of worm infestations.
|
T12675L |
PT2399
|
1672662-14-4
|
98%
|
|
PT2399 shows effective antitumor activity in vivo. PT2399 is an effective and selective HIF-2α antagonist, which directly binds to the HIF-2α PAS B domain (IC50:...
|
T6823 |
E3330
|
136164-66-4
|
98%
|
|
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
|
T7880 |
IOX4
|
1154097-71-8
|
98%
|
|
IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)
|
T2445 |
FG-2216
|
223387-75-5
|
98%
|
|
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction...
|