Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that bl...
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a...
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest. |
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1. |
Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic ...