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Membrane transporter/Ion channel CRM1

CRM1

Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is a eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.
Cat No. product name
T11837 Leptomycin A Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blo...
T14885 CBS9106 CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...
T6106 Selinexor Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic a...
T6074 KPT276 KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
T2425 KPT185 KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
Leptomycin A
T11837CAS 87081-36-5
Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blo...
CBS9106
T14885CAS 1076235-04-5
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...
Selinexor
T6106CAS 1393477-72-9
Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic a...
KPT276
T6074CAS 1421919-75-6
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
KPT185
T2425CAS 1333151-73-7
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.