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Membrane transporter/Ion channel CRM1

CRM1

Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is a eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.
Cat No. product name
T11837 Leptomycin A Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that bl...
T14885 CBS9106 CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a...
T2425 KPT185 KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
T6074 KPT276 KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
T6106 Selinexor Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic ...
Leptomycin A
T11837CAS 87081-36-5
Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that bl...
CBS9106
T14885CAS 1076235-04-5
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a...
KPT185
T2425CAS 1333151-73-7
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
KPT276
T6074CAS 1421919-75-6
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
Selinexor
T6106CAS 1393477-72-9
Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic ...