T14885 |
CBS9106
|
1076235-04-5
|
98%
|
|
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...
|
T11837 |
Leptomycin A
|
87081-36-5
|
98%
|
|
Leptomycin A, a metabolite derived from Streptomyces, acts as an inhibitor of CRM1 (exportin 1) and effectively suppresses HIV-1 replication. Compared to Leptomy...
|
T15735 |
Leptomycin B
|
87081-35-4
|
98%
|
|
Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inact...
|
T6106 |
Selinexor (KPT-330)
|
1393477-72-9
|
98%
|
|
Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic a...
|
T6123 |
Verdinexor
|
1392136-43-4
|
98%
|
|
Verdinexor (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
|
T6074 |
KPT276
|
1421919-75-6
|
98%
|
|
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
|
T2425 |
KPT185
|
1333151-73-7
|
98%
|
|
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
|
T1844 |
KPT330,(E)-
|
1421923-86-5
|
98%
|
|
KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothel...
|