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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17103 | TM-N1324 | Others , GHSR | |
TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s... | |||
T4648 | TC-G-1008 | GPR39-C3 | GHSR |
TC-G-1008 (GPR39-C3) is a GPR39 (zinc receptor) agonist (EC50 values are 0.4 and 0.8 nM for rat and human receptors respectively). | |||
TQ0022 | Capromorelin Tartrate | CP 424391-18 | GHSR |
Capromorelin Tartrate (CP 424391-18) is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a). | |||
T16508 | PF-5190457 | PF-05190457 | GHSR |
PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36). | |||
T10319 | Anamorelin | RC-1291,ONO-7643 | GHSR |
Anamorelin (ONO-7643) is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay). | |||
T1088 | Repaglinide | AG-EE 388 ZW,AG-EE 623ZW | Potassium Channel , PPAR |
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare... | |||
T7112 | Ibutamoren Mesylate | MK-0677,MK-677 | GHSR |
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. | |||
T7225 | AnaMorelin hydrochloride | RC-1291 hydrochloride,ONO-7643 hydrochloride | GHSR |
AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay). | |||
TN1128 | Bruceine E | Others | |
Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue. | |||
T11719 | JMV 2959 hydrochloride (925238-89-7 free base) | JMV 2959 hydrochloride | GHSR |
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells. | |||
TP2328L | CJC-1295 acetate(863288-34-0 free base) | DAC:GRF acetate | GHSR |
CJC-1295 acetate(863288-34-0 free base) (DAC:GRF acetate) is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS) | |||
T20095 | Ibutamoren | MK 677,L 163191,L-163191,L163191,MK677,MK-677 | Others |
Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It also alters the metabolism of body fat and so may... | |||
T34281 | Relamorelin | BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 | GHSR |
Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ... | |||
T11798 | L-692429 | MK-0751 | GHSR , GPCR19 |
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G prot... | |||
T32507 | L-739943 | L 739943,L739943 | |
L-739943 is a growth hormone secretagogue. | |||
T32435 | L 163255 | L-163255,L163255,L163,255,L-163,255,L 163,255 | |
L 163255 is a type of growth hormone secretagogue (GHS). | |||
T31734 | BMS-604992 | EX1314,EX-1314 HCl,EX-1314,BMS604992,EX-1314 hydrochloride, BMS-604992,EX 1314 | |
EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist. | |||
T28812 | SM-130686 | SM 130686,SM130,686,SM 130,686 | |
SM-130,686 is a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue. It has around half the potency of the endogenous agonist ghrelin as a stimulator o... | |||
T11719L | JMV 2959 | Others | |
JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM). | |||
T30513 | BMS-317180 | BMS317180 | |
BMS-317180 is a potent, novel, orally effective growth hormone secretagogue (GHS) that shows an excellent safety profile in preclinical studies. The compound was advanced into clinical development. |