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Search Results for " secretagogue "

20

Compounds

Cat No. Product Name Synonyms Targets
T17103 TM-N1324 Others , GHSR
TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s...
T4648 TC-G-1008 GPR39-C3 GHSR
TC-G-1008 (GPR39-C3) is a GPR39 (zinc receptor) agonist (EC50 values are 0.4 and 0.8 nM for rat and human receptors respectively).
TQ0022 Capromorelin Tartrate CP 424391-18 GHSR
Capromorelin Tartrate (CP 424391-18) is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a).
T16508 PF-5190457 PF-05190457 GHSR
PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36).
T10319 Anamorelin RC-1291,ONO-7643 GHSR
Anamorelin (ONO-7643) is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
T1088 Repaglinide AG-EE 388 ZW,AG-EE 623ZW Potassium Channel , PPAR
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare...
T7112 Ibutamoren Mesylate MK-0677,MK-677 GHSR
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
T7225 AnaMorelin hydrochloride RC-1291 hydrochloride,ONO-7643 hydrochloride GHSR
AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).
TN1128 Bruceine E Others
Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.
T11719 JMV 2959 hydrochloride (925238-89-7 free base) JMV 2959 hydrochloride GHSR
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
TP2328L CJC-1295 acetate(863288-34-0 free base) DAC:GRF acetate GHSR
CJC-1295 acetate(863288-34-0 free base) (DAC:GRF acetate) is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS)
T20095 Ibutamoren MK 677,L 163191,L-163191,L163191,MK677,MK-677 Others
Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It also alters the metabolism of body fat and so may...
T34281 Relamorelin BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 GHSR
Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ...
T11798 L-692429 MK-0751 GHSR , GPCR19
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G prot...
T32507 L-739943 L 739943,L739943
L-739943 is a growth hormone secretagogue.
T32435 L 163255 L-163255,L163255,L163,255,L-163,255,L 163,255
L 163255 is a type of growth hormone secretagogue (GHS).
T31734 BMS-604992 EX1314,EX-1314 HCl,EX-1314,BMS604992,EX-1314 hydrochloride, BMS-604992,EX 1314
EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist.
T28812 SM-130686 SM 130686,SM130,686,SM 130,686
SM-130,686 is a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue. It has around half the potency of the endogenous agonist ghrelin as a stimulator o...
T11719L JMV 2959 Others
JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).
T30513 BMS-317180 BMS317180
BMS-317180 is a potent, novel, orally effective growth hormone secretagogue (GHS) that shows an excellent safety profile in preclinical studies. The compound was advanced into clinical development.
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