non-functional — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3474	RO 46-8443		Endothelin Receptor
	RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.		Endothelin Receptor
T18562	Propargyl-NH-PEG3-C2-NHS ester		Others
	Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker with propargyl and N-hydroxysuccinimide functional groups. It is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T32004	GSK172981	GSK 172981,GSK-172981
	GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional e...
T62973	DS-3801b
	DS-3801b is a potent, non-macrolide GPR38 agonist and has the potential to be a novel gastrointestinal agonist for the study of functional gastrointestinal disorders (e.g. gastroparesis, chronic constipation).
T36934	PK7242 (maleate)	PK7242 (maleate)
	The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further prolife...
T70456	Nolpitantium Free Base
	Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal s...
T38844	MK-8245 Trifluoroacetate
	MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect...

Compounds

RO 46-8443

T3474

Synonym:

Target: Endothelin Receptor

Propargyl-NH-PEG3-C2-NHS ester

Synonym: GSK 172981,GSK-172981

Synonym: PK7242 (maleate)

Target:

Nolpitantium Free Base

T70456

Synonym:

Target:

MK-8245 Trifluoroacetate

T38844

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01854	DPP10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPJ-01461	IL-15RA & IL-15 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPJ-01462	IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPH-00552	Lpp Protein, Erwinia amylovora, Recombinant (His & SUMO)	Erwinia amylovora	E. coli
	A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds ...
TMPJ-00812	HBQ1 Protein, Human, Recombinant (His)	Human	E. coli
	Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is originally found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. Theta-1 i...
TMPH-02380	RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)	Kluyveromyces marxianus	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precurs...
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a pap...
TMPH-02300	RAD23A Protein, Human, Recombinant (His)	Human	E. coli
	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chain...
TMPY-05353	CCL26 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),...
TMPH-00651	Lpp Protein, E. coli, Recombinant (His & KSI)	E. coli	E. coli
	An outer membrane lipoprotein that controls the distance between the inner and outer membranes; adding residues to Lpp increases the width of the periplasm. The only protein known to be covalently linked to the peptidogl...
TMPH-02169	TRBC1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02173	TRBC2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPY-04562	GRK2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, inte...
TMPH-02168	TRAC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPH-02271	BTK Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activatio...