monooxygenase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1576	Diallyl disulfide		IL Receptor , NOS , NF-κB
	Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.		IL Receptor , NOS , NF-κB
T19654	Guanoclor	VATENSOL	Others
	Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.		Others
T13383	Zamicastat	BIA 5-1058	BCRP , Hydroxylase , P-gp
	Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).		BCRP , Hydroxylase , P-gp
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
T7877	Thiacetazone	Diazam,Thioacetazone,Neustab,Neotibil	Others , Antibacterial , Antibiotic
	Thiacetazone (Diazam) is a thiosemicarbazone that thioacetazone treatment of pulmonary tuberculosis		Others , Antibacterial , Antibiotic
T6604	Nepicastat hydrochloride	Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl	Hydroxylase
	Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta...		Hydroxylase
T20373	1-Phenylpyrrole	NSC16581,NSC-16581,NSC 16581	Others
	1-Phenylpyrrole (NSC-16581) is an inhibitor of CYP450 dependant monooxygenase activity in microsomes from rat liver.		Others
T20700	Racemetirosine		Others
	Racemetirosine is an inhibitor of Tyrosine 3-monooxygenase, and consequently it inhibits the synthesis of catecholamines.		Others
T0293	Metyrapone	NSC-25265,Su-4885	Others , P450 , Dehydrogenase , Autophagy
	Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.		Others , P450 , Dehydrogenase , Autophagy
T4829	3-Hydroxyphenylacetic acid		Others , Endogenous Metabolite
	3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyro...		Others , Endogenous Metabolite
T11680	Isoasatone A		P450
	Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.		P450
TP1344	Luciferase		Others
	Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac...		Others
TN1078	Seneciphylline		P450 , GST
	Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat...		P450 , GST
T28202	NSC-152035	Racemetirosine methyl ester HCl,NSC 152035,Racemetirosine methyl ester hydrochloride
	NSC-152035 is an inhibitor of tyrosine 3-monooxygenase.
T32743	Licodione
	Licodione is a Cytochrome P450 Monooxygenase Catalyzing 2-Hydroxylation of 5-Deoxyflavanone.
T70041	GSK065
	GSK065 is a potent inhibitor of kynurenine-3-monooxygenase (KMO).
T13258L	UPF-648		Others
	UPF-648 is a potent kynurenine 3-monooxygenase inhibitor. It also shows highly active at 1 uM (81 ± 10% KMO inhibition).		Others
T13258	UPF-648 sodium salt		Others
	UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).		Others
T11470	GSK 366		Hydroxylase
	GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).		Hydroxylase
T0293L	Metyrapone Tartrate	SU 4885,Metopirone tartrate,SU-4885,SU4885
	Metyrapone Tartrate is an inhibitor of the STEROID 11-beta-monooxygenase enzyme which is used as a test for feedback hypothalamic-pituitary mechanism in the diagnosis of Cushing SYNDROME.