mold

Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil is a broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea.

Moldapyranone A is a natural product that can be used in related research in the field of life sciences. Its product number is TN8808.

Moldapyranone B is a natural product that can be used in related research in the field of life sciences. Its product number is TN8809.

Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Sorbic acid is a natural product that inhibits various bacteria, including sporeformers,

Methocarbamol (T1409) is a central muscle relaxant. Methocarbamol-D5 is deuterium labeled Methocarbamol.

Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).

Salbutamol-D9 is a deuterated compound of Salbutamol. Salbutamol (T1139) has a CAS number of 18559-94-9. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

Thymol-D13 is the deuterated analog of Thymol. Thymol (T3S0717) is a major monoterpenol found in essential oils derived from plants belonging to the Lamiaceae family, as well as other families such as Verbenaceae, Scrophulariaceae, and Ranunculaceae. It exhibits antioxidant, anti-inflammatory, antibacterial, and antifungal properties.

Salbutamol-D3 is a deuterated compound of Salbutamol. Salbutamol (T1139) has a CAS number of 18559-94-9. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

Salbutamol-D3 (Standard) is the standard substance of Salbutamol-D3, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Salbutamol-D3 is a deuterated compound of Salbutamol. Salbutamol (T1139) has a CAS number of 18559-94-9. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.

Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.

Royal Jelly Acid (Queen Bee Acid) is a major fatty acid found in royal jelly that promotes neuronal growth and protection and reduces anxiety. Royal Jelly Acid induces reactive oxygen species (ROS)-mediated apoptosis in A549 cells, improves non-alcoholic fatty liver disease by activating the AMPK-α signaling pathway, and reduces bone loss by inhibiting the NF-κB signaling pathway downstream of FFAR4. Royal Jelly Acid also exhibits inhibitory effects against various bacteria and fungi, including Aspergillus niger, mold, and Staphylococcus aureus. By targeting aspartyl β-hydroxylase and inhibiting chondrocyte senescence, Royal Jelly Acid exerts a preventive and therapeutic effect against osteoarthritis.

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.

Monascin, an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice), exhibits anti-tumor-initiating and anti-inflammatory activities.

Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.

Dibenzylideneacetone (DBA) is an antifungal agent that exhibits inhibitory activity against Botrytis cinerea Chitinase with an IC50 of 13.10 µg/mL. It has a minimum inhibitory concentration (MIC) against B. cinerea of 32 µg/mL. The EC50 values for inhibiting mycelial growth and spore germination are 16.29 µg/mL and 14.64 µg/mL, respectively. Dibenzylideneacetone effectively combats grey mold infection in cherry tomatoes by inhibiting chitinase activity.

CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.

CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.

2-Pentanone is a five-carbon ketone volatile organic compound that occurs naturally in the plant Nicotiana tabacum (Tobacco) and in blue cheese as a metabolic product of Penicillium mold growth during the ripening process.

Antifungalagent 102 (compound C20) is an agent effective against gray mold with an EC50 value of 1.23 μg/mL.

CMLD009688 is a cationic amphiphilic antifungal agent. It selectively inhibits phytopathogenic fungi, such as Fusarium graminearum. CMLD009688 interacts with biological membranes, disrupting vacuole and mitochondrial membrane structures, leading to fungal cell death. This compound shows potential for research in plant fungal diseases, including wheat scab and gray mold.