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Results for "

inflammatory bowel diseases

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    11
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    1
    TargetMol | Peptide_Products
  • Recombinant Protein
    5
    TargetMol | Recombinant_Protein
Elubrixin
SB-656933
T11179688763-64-6In house
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
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6-8 weeks
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Izilendustat
T643361303512-02-8
Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate inhibit of human recombinant EGLN-1 as substrate after 20 mins by mass spectrophotometric analysis.
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TargetMol | Inhibitor Sale
Vercirnon
CCX282-B, GSK-1605786, Traficet-EN
T17225698394-73-9
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
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TargetMol | Inhibitor Sale
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
GDC046
T223381258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.
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TargetMol | Inhibitor Sale
Elubrixin tosylate
SB-656933 tosylate,Elubrixin tosylate
T41121960495-43-6
Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 and IL-8 receptor antagonist. It effectively inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). This compound holds promise for studying inflammatory diseases, including inflammatory bowel disease and airway inflammation.
    7-10 days
    Inquiry
    tcjl37
    T46661258294-34-6
    TCJL37, a potent, selective, and orally bioavailable inhibitor of TYK2, exhibits a K i value of 1.6 nM. It is useful for researching inflammatory bowel diseases (IBD) [1].
    • Inquiry Price
    8-10 weeks
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    CCR6 antagonist 1
    T60145588674-64-0
    CCR6 antagonist 1, a chemical compound acting as a CCR6 antagonist, effectively inhibits the CCL20 CCR6 axis. Its utility lies in research focused on autoimmune-mediated inflammatory diseases, including inflammatory bowel diseases (IBDs).
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    Mercaptoethylguanidine (MEG) (dihydrobromide)
    T6053032665-11-5
    Mercaptoethylguanidine (MEG) dihydrobromide is a selective inducible nitric oxide synthase inhibitor and peroxynitrite scavenger with potential for inflammatory bowel diseases research.
    • Inquiry Price
    6-8 weeks
    Size
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    Izilendustat hydrochloride
    T630351303513-80-5
    Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase that stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) and hypoxia-inducible factor-2 (HIF-2), with potential applications in HIF-1α-related diseases, including peripheral vascular disease (PVD), heart failure, coronary artery disease (CAD), ischaemia, anaemia, colitis, and other inflammatory bowel diseases.
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    1-2 weeks
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    LON63114
    T711791229363-11-4
    LON63114, also known as FFA2-Agonist-1 is a selective orthosteric agonist of human FFA2. FFA2-Agonist-1 is potentially useful in the treatment of gastrointestinal disorders and inflammatory bowel diseases. LON63114 was reported in WO2011076732. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https: www.medkoo.com page naming).
    • Inquiry Price
    6-8 weeks
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    d-GLP-2 E33A
    TP2967
    d-GLP-2 E33A is an agonist of the glucagon-like peptide 2 receptor (GLP-2R) with an EC50 of 414 nM. It activates GLP-2R and enhances the phosphorylation of AKT without stimulating GLP-1R. d-GLP-2 E33A is used for research in conditions such as malabsorption and inflammatory bowel diseases.
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