fes

AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).

AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).

AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer.

Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo into its active metabolite 5-hydroxymethyl tolterodine, which binds and inhibits muscarinic receptors on the bladder detrusor muscle, thereby preventing bladder contractions or spasms caused by acetylcholine.

Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.

Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).

Etofesalamide is a non-steroidal anti-inflammatory drug. In filamentous fungi, its primary Phase II metabolites include glucosides and nucleoside conjugates (e.g., etofenamate-2-glucuronide). Etofesalamide can be utilized in research concerning allergic and autoimmune dermatological conditions, such as acne, psoriasis, and contact dermatitis.

DE(isopropyl)desfesoterodine is a biochemical.

Mefeserpine is a biochemical.

CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.

Desfesoterodine fumarate is a bio-active chemical. Detailed information has not been published.

16-O-Methylcafestol, a cafestol derivative, is isolatable from green coffee beans [1].

Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).

Vepafestinib is an orally administered, highly selective, ATP-competitive RET kinase inhibitor that effectively suppresses both wild-type RET and key drug-resistant mutations (V804, G810, L730). Vepafestinib exhibits blood-brain barrier penetration and high kinase selectivity. It is suitable for use in tumor research.

16-O-Methylcafestol (Standard) is a reference standard for research and analysis in studies involving 16-O-Methylcafestol. 16-O-Methylcafestol, a cafestol derivative, is isolatable from green coffee beans [1].

CAFESTOL (Standard) is a reference standard for research and analysis in studies involving CAFESTOL. CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.

Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.

Desisopropyl-fesoterodine (compound 1) is the oxidative N-dealkylation product of the tertiary amine functional group in Fesoterodine, and also serves as a degradation product of Fesoterodine (compound PP-6).

Ifebemtinib (BI-853520) is a small-molecule inhibitor, a highly potent FAK inhibitor (IC50=1 nM) with oral efficacy and antiproliferative activity, used in tumor research including breast cancer and ovarian cancer. It exhibits significant antiproliferative activity.

Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-mediated Fe-S cluster biosynthesis.

Ifebemtinib FA (BI-853520 FA) is an orally active and potent inhibitor of adhesion patch kinase (FAK) with anticancer and antiproliferative activity for the study of ovarian and lung cancer.

Chlorothalonil (DAC 2787) is a broad-spectrum fungicide with high efficiency and low toxicity. Chlorothalonil is widely used to control various pests such as fruit trees and vegetable leaves. Chlorothalonil also has good control effects on various diseases such as rice, wheat, and cotton.

Dymanthine (ADMA 18) is an agent of veterinary anthelmintic.

Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.