dgtp

dGTP (2'-Deoxyguanosine-5'-triphosphate) is a guanosine nucleotide highly susceptible to oxidative damage, resulting in 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.

7-Deaza-7-propargylamino-dGTP is a dGTP analogue specifically engineered for gene sequencing.

7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is a widely used deoxyguanosine triphosphate (dGTP) analog in next generation sequencing (NGS).

7-Deaza-dGTP tetralithium is utilized for the amplification of GC-rich DNA sequences [1].

3'-Amino-3'-deoxyguanosine-5'-O-triphosphate (3'-amino-dGTP), an amine-modified nucleotide, effectively terminates RNA strand synthesis as catalyzed by RNA polymerase in E. coli. This compound has also been utilized in creating a non-hydrolyzable derivative of the alarmone guanosine pentaphosphate (pppGpp).

3'-Amino-3'-dGTP tetrasodium serves as an analog of GTP, generated by the insertion of an amino group at the C3 position of GTP.

3'-ONH2-dGTP sodium solution (100mM) is a labeled modified deoxynucleotide (dNTP) that releases pyrophosphate to produce fluorescence, offering specialized applications in gene synthesis and sequencing.

7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP. It is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used in gene sequencing.

3'-Amino-3'-dGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-P-dGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-O-Methylthiomethyl-dGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-Azidomethyi-dGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].

7-Deaza-7-propargylamino-ddGTP is a gene sequencing analog of dideoxyguanosine triphosphate (ddGTP).

7-Deaza-7-propargylamino-ddGTP 3TEA is a derivative and modified nucleotide of ddGTP, used in gene sequencing. ddGTP is one of the chain terminators used in Sanger sequencing.

ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) is a type of 2',3′-dideoxyribonucleoside 5'-triphosphate (ddNTP) that functions as a chain-elongating inhibitor of DNA polymerase in DNA sequencing.

2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) trisodium, a member of the 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs), functions as a chain-elongating inhibitor of DNA polymerase, pivotal for DNA sequencing. It operates either as an inhibitor or a substrate for DNA polymerase α [1] [2] [3].

3′-Azido-ddGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-NH2-ddGTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

dGTPαS sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

TH7127 is a selective inhibitor of the sterile alpha motif and histidine-aspartate domain-containing protein-1 (SAMHD1), inhibits hydrolysis of ara-CTP and Cl-F-ara-ATP, and inhibits the enzymatic activity of SAMHD1 on dGTP, Cl-F-ara-ATP, and ara-CTP.

Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.

Forodesine (BCX-1777) is an orally active and potent purine nucleoside phosphorylase (PNP) inhibitor, a new purine nucleoside analog, inhibitor of human lymphocyte proliferation, induces apoptosis in leukemic cells by increasing dGTP levels, and may be useful in the study of cutaneous T-cell lymphomas.