aoa

Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and streptococcus. The drug takes effect as the inhibitor of the initiation of bacterial protein synthesis.

Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.

TAOA AM Ester trimethyl lock is a high-affinity fluorescent prodrug-like inhibitor of excitatory amino acid transporters (EAAT). It is capable of crossing cell membranes and is activated by hydrolysis from endogenous cellular esterases to form an active EAAT inhibitor. TAOA AM Ester trimethyl lock is useful for studying neurodegeneration and neuronal cell death.

MAOA-IN-1 (compound 15) is an orally-active monoamine oxidase A (MAOA) inhibitor with cytotoxic effects on prostate cancer cells. It exhibits Caco-2 permeability and reduced central nervous system (CNS) permeability, indicating potential utility in anti-cancer and anti-inflammatory research [1].