Rhamnaceae

Jujuboside A, a glycoside extracted from Semen Ziziphi Spinosae, exhibits neurophysiological inhibitory effects and is considered a potential therapeutic agent for the treatment of Alzheimer's disease.

L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.

Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.

Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.

Frangulin A protects Vitis vinifera leaves from Plasmopara viticola infection and inhibits the first stage of biotrophic hyphal development of P. Viticola.

(-)-Verbenone is a naturally occurring terpene found in the leaves of Suregada zanzibariensis Verdc.Verbenone has anti-aggregation pheromone effects and interrupts the attraction of bark beetles to its aggregation pheromone.

Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) is a flavonol glycoside extract used as an anti-oxidant.

Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.

1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.

Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.

5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.

Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.

6‴-Feruloylspinosin (6'''-Feruloylspinosin) may possess anti-inflammatory activity.

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction

Rhamnazin (3',7-Dimethylquercetin) is an orally active VEGFR2 signaling inhibitor with anti-angiogenesis, anti-tumor, antioxidant, and anti-inflammatory activities. It inhibits VEGFR2 kinase and is used for leukemia research.

Casanthranol, a concentrated mixture of anthranol glycosides from the dried bark of Rhamnus p. (cascara sagrada), is a stimulant laxative used to alleviate constipation and other medical conditions by increasing muscle contractions in the intestinal wall to facilitate bowel movements.

Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.

13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits antilung and antilaryngeal cancer ac

Jujuboside D shows lipoxygenase-inhibiting activity.

2,3-O-Isopropylidenyl euscaphic acid exhibits a potent hepatoprotective effect, with an EC50 value of 88.36±3.25 μM in Hep G2 cells.

Rhamnocitrin 3-apiosyl-(1→2)-glucoside is a natural product for research related to life sciences. The catalog number is TN6650 and the CAS number is 148031-68-9.

5'''-O-Feruloyl complanatoside B is a natural product used in life sciences research (catalog number: TN6649, CAS number: 142473-98-1).

Frangulin B is a natural product for research related to life sciences. The catalog number is TN4079 and the CAS number is 14101-04-3.

Catharticin is a natural product for research related to life sciences. The catalog number is TN3611 and the CAS number is 39723-40-5.