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Natural Product Categories Natural Product Categories Lamiales
Lamiales is a large and highly significant order of flowering plants that includes families such as Lamiaceae, Oleaceae, and Plantaginaceae, encompassing many medicinal and aromatic plants like mint, lavender, olive, and sesame. Members of Lamiales are rich in diverse secondary metabolites, including terpenoids, flavonoids, iridoids, phenylethanoids, and alkaloids. In biomedical research, Lamiales is one of the most important orders due to its broad pharmacological spectrum, including anti-inflammatory, antimicrobial, neuroprotective, anticancer, and metabolic regulatory activities. Many essential oils and herbal medicines originate from this order, making it central to phytotherapy and natural product drug discovery. Its chemical diversity and global distribution make Lamiales a cornerstone of modern medicinal plant research.
- BaicalinBaicalein 7-O-β-D-glucuronideT277521967-41-9Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from Scutellaria baicalensis that exhibits anti-inflammatory, antioxidant, antitumor, and antiviral activity. Baicalin can be used in research on inflammation, neurodegenerative diseases, tumors, and metabolic syndrome.
- $31
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Cited - SyrosingopineTN225284-36-6Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux. Syrosingopine is an orally available antihypertensive drug with potential for cancer research in combination with metformin.
- $61
SizeQTY Cited - PonicidinRubescensine BT2S197552617-37-5Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens that exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on the protein levels of JAK2 and STAT3.
- $55
SizeQTY - EchinacosideT171682854-37-3Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilative ones.
- $37
SizeQTY Cited - Salvianolic acid ETN2174142998-46-7Salvianolic acid E is a water-soluble constituent isolated from Salvia miltiorrhiza.
- $297
SizeQTY - CholesterolCholesteryl alcohol, CholesterinT076057-88-5Cholesterol is the primary sterol in mammals, accounting for approximately 20–25% of the plasma membrane structure. It plays a key role in regulating membrane fluidity, permeability, and protein function. As an endogenous agonist of estrogen-related receptor α (ERRα), cholesterol is widely involved in metabolic regulation and serves as a precursor for the synthesis of hormones and bile acids. It is commonly used in experimental models of hyperlipidemia.
- $43
SizeQTY Cited - Eriocalyxin BTN162084745-95-9Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly target
- $313
SizeQTY - LasiodinLasiokaurinTN185428957-08-6Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor and antibacterial activities, induces cell cycle length and apoptosis, induces cell migration and invasion, and can be used in the study of nasopharyngeal carcinoma.
- $126
SizeQTY - Salvianolic Acid CT3149115841-09-3Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia.
- $36
SizeQTY Cited - MOSLOFLAVONET5779740-33-0MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
- $40
SizeQTY Cited - Skullcapflavone IITN104055084-08-7Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma.Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG
- $85
SizeQTY - Salvianolic acid ADan Phenolic Acid AT6S044496574-01-5Salvianolic acid A (Dan Phenolic Acid A) is a natural product and an inhibitor of matrix metalloproteinase 9 (MMP-9). Salvianolic acid A has antioxidant and anti-inflammatory activity and protects the blood-brain barrier.
- $45
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Cited - Baicalein5,6,7-TrihydroxyflavoneT2858491-67-8Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
- $30
SizeQTY Cited - 6-Hydroxyluteolin 7-glucosideTN131554300-65-16-Hydroxyluteolin 7-glucoside is derived from Tanacetum parthenium and T. vulgare showing anti-inflammatory effects.
- $139
SizeQTY - Viscidulin IIIGanhuangeninTN230292519-91-0Viscidulin III (Ganhuangenin) is present in Scutellaria baicalensis and acts as an α-glucosidase inhibitor.
- $73
SizeQTY - Glaucocalyxin BTQ030980508-81-2Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).
- $98
SizeQTY - Carnosic acidT49573650-09-7Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.
- $40
SizeQTY Cited - AndropanolideTQ0073869807-57-8Andropanolide is a dipterocarbon from Andrographis paniculata with anti-HIV, antimalarial and anticancer activities and inhibits Lipopolysaccharides (LPS)-stimulated overproduction of nitric oxide (NO) in RAW264.7 macrophages.
- $147
SizeQTY - CarnosolT6S13025957-80-2Carnosol is an Nrf2 activator, increasing Nrf2 levels and promoting heme oxygenase 1 (HMOX1) expression. It is a ribosomal S6 kinase (RSK2) inhibitor and can be used in gastric cancer-related research with an IC50 value of approximately 5.5 μM.
- $39
SizeQTY Cited - CostunolideNSC 106404, Costus lactone, (+)-CostunolideT2902553-21-9Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
- $30
SizeQTY Cited - 9'''-Methyl salvianolate B9'''-MethyllithosperMate BT45891167424-32-99'-Methyllithospermate B is a natural extract obtained from Cynoglossum columnae.
- $38
SizeQTY - (+)-AromadendreneT8247489-39-4(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
- $30
SizeQTY - OridoninRubescensin A, Rubescenin, NSC-250682, IsodonolT279028957-04-2Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.
- $44
SizeQTY Cited - HirsuteineTN108135467-43-7Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.
- $52
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