PKA

protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase . Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

Cat. No.	Product name	CAS No.	Purity
TQ0072	Warangalone	4449-55-2	98%
TQ0072	Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with ...
T6139	A-674563	552325-73-2	98%
T6139	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
TN4317	Isopedicin	4431-42-9	98%
TN4317	Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
TP1351	Kemptide	65189-71-1	98%
TP1351	Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).
TN4277	Isocupressic acid	1909-91-7	98%
TN4277	Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
T15669	KT5720	108068-98-0	98%
T15669	KT5720 is a cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (PKA) (Ki: 60 nM).
TN3383	α-Amyrin palmitate	22255-10-3	98%
TN3383	alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin ...
TN1542	Cycloheterophyllin	36545-53-6	98%
TN1542	Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be u...
T1606	Fasudil	103745-39-7	98%
T1606	Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T77504	2,4-Dichlorothieno[3,2-d]pyrimidine	16234-14-3	98%
T77504	2,4-Dichlorothieno[3,2-d]pyrimidine is a potent protein kinase inhibitor.2,4-Dichlorothieno[3,2-d]pyrimidine has antitumor activity that inhibits the growth of a...
T15374	Ipatasertib dihydrochloride	1396257-94-5	98%
T15374	Ipatasertib dihydrochloride is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively).
T4444	A-674563 HCl (552325-73-2(free base))		98%
T4444	A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 ...
T8681	HA-1004 dihydrochloride	92564-34-6	98%
T8681	HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
T3269	Metadoxine	74536-44-0	98%
T3269	Metadoxine is a neurotransmitter stimulant.
TP1789L	Malantide acetate(86555-35-3 free base)	TP1789L	98%
TP1789L	Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide tha...
TN4114	Gardenin A	21187-73-5	98%
TN4114	Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
TP1876L	CREBtide acetate(149155-45-3 free base)	TP1876L	98%
TP1876L	CREBtide acetate is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).
T21983L	PKI 14-22 amide, myristoylated Acetate	T21983L	98%
T21983L	PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.
T16791	Rottlerin	82-08-6	98%
T16791	Rottlerin is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-...
TP1523	PKG inhibitor peptide TFA (82801-73-8 free base)	TP1523	98%
TP1523	PKG inhibitor peptide TFA is an inhibitor of atp-competitive cGMP-dependent protein kinase (PKG), Ki 86 μM.