terpenoid

Penisterpenoid A (Compound 1), an activator of the PINK1 Parkin mitochondrial autophagy signaling pathway, is derived from the rhizosphere fungi of the medicinal plant Bupleurum. In both in vitro and in vivo settings, Penisterpenoid A effectively reduces lipid accumulation and significantly enhances mitochondrial function.

α-Terpinene is a terpenoid,has acaricidal, antiprotozoal, and antioxidant properties

Palbinone, a terpenoid isolated from the roots of Paeonia albiflora Pallas, exhibits anti-inflammatory activity.

Azadirachtin B (Deacetylazadirachtinol) is a terpenoid compound isolated from Azadirachta seeds, with insecticidal, anticancer, anti-inflammatory, antitumor, and antiviral activities, useful in the study of viral infections. Azadirachtin B also has osteoblast proliferation, differentiation, and mineralization properties.

Chamazulene (Dimethulene) is a terpenoid obtained from Matricaria chamomilla L.. It possesses anti-inflammatory and antioxidant activity, inhibits leukotriene B4 formation and can be used in the study of melanoma.

Terpinyl Butyrate is a terpenoid ester widely used in biochemical experiments and drug synthesis research.

Lochnerine is an alkaloid of terpenoid indole.

Ganoderic acid J, a natural terpenoid extracted from Ganoderma lucidum fungus, exhibits anti-inflammatory properties.

Bisabolone oxide A is a terpenoid isolated from Matricaria chamomilla L. It reduces neuronal excitability.Bisabolone oxide A inhibits α glucokinase and has been shown to inhibit α glucokinase in Helicoverpa armigera, Aedes vittatus, and Anopheles subpictus larvae and showed biotoxicity in Helicoverpa armigera, Aedes vittatus and Anopheles subpictus larvae experiments.

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product with significant pharmacological effects on the cardiovascular system.

Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg mL, as demonstrated in its impact on Meth-A tumor cells.

Sinulatumolin E (compound 6), a terpenoid, exhibits significant anti-inflammatory properties by inhibiting TNF-α with an IC50 value of 3.6 μM.

Forrestiacid K, a terpenoid derived from Pseudotsuga forrestii, functions as an inhibitor of ATP-citrate lyase (ACL) [1].

Mahanimbidine, a terpenoid alkaloid, is extractable from the leaves and stem bark of Murraya koenigii Spreng [1] [2].

Isogermafurenolide, a cytotoxic terpenoid isolated from the wood of Vepris punctata in the Madagascar Rainforest [1], exhibits potential antineoplastic properties.

(+)-Isopulegol is a monoterpenoid from Mentha canadensis L.

8-Hydroxy-9,10-diisobutyryloxy-thymol, a potent terpenoid found in Inula sericophylla [1], exhibits significant bioactivity.

Alphitolic acid, a terpenoid from Potentilla freyniana Bornm, is a selective 3-hydroxy-3-methylglutamic acid coenzyme-A synthase 2 (HMGCS2) inhibitor with anti-inflammatory and anticancer activity that inhibits T cell proliferation in a concentration-dependent manner. Alphitolic acid induces apoptosis and autophagy.

Licoricesaponin A3 is a terpenoid saponin extracted from Gymnostachyum febrifugum Benth., which has good affinity for 5-LOX receptors.

Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside G is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside C is a quassinoid and terpenoid extracted from Brucea javanica that has the potential to inhibit InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and to act as an anti-tuberculosis (TB) drug potential.

Yadanzioside F is a quassinoid and terpenoid extracted from the seed of Crowberry (Brucea javanica), which is lethally toxic to mice and has the potential to inhibit the enzyme InhA (Mycobacterium enoyl acyl carrier protein reductase) and to act as an antituberculosis (TB) agent.

Terretonin, a fungal terpenoid isolated from Aspergillus terreus, undergoes a biosynthetic pathway involving multiple enzymes. Cytochrome P450 Trt6 catalyzes the oxidation of terrenoid to form an unstable intermediate. This intermediate is subsequently catalyzed by isomerase Trt14 and processed by non-heme iron-dependent dioxygenase Trt7, completing the biosynthesis of terretonin [1].