substitute

D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose and isomer of D-galactose, occurs naturally in Sterculia setigera gum and is found in small quantities in various foods such as sterilized and powdered cow's milk, hot cocoa, and various cheeses, yogurts, and other dairy products. It can be synthesized from D-galactose by isomerization under alkaline conditions in the presence of calcium. D-Tagatose has numerous health benefits, including promotion of weight loss, no glycemic effect, anti-plaque, non-cariogenic, anti-halitosis, prebiotic, and anti-biofilm properties; it is beneficial for organ transplants, enhancement of flavor, improvement of pregnancy and fetal development, treatment of obesity, and reduction in symptoms associated with type 2 diabetes, hyperglycemia, anemia, and hemophilia. (PMID: 17492284).

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Substituted piperidines-1 can promote the release of growth hormone in humans and animals.

Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide.

SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.

Lenacil (634 Hexilure) is an agent of herbicide.Lenacil can inhibit photosynthesis.

SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.

T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.

EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.

Tung oil is an oil extracted from the seeds of the tung tree.

Maltitol (4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute.

Perfluamine (FTPA) is a hydrophobic carrier fluid and can be used as a blood substitute.

PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose. PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener.

Tripotassium phosphate is a strongly alkaline inorganic salt commonly used as a stabiliser, buffer, and phosphate substitute, widely used in biochemical experiments and drug synthesis research.

Macitentan-D4 is a deuterated substitute for Macitentan (T2561) and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-D4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.

RS-246204 is an R-spondin-1 substitute compound capable of initiating and sustaining intestinal organoids in R-spondin-1-deficient media, activating R-spondin-dependent pathways in DSS-induced colitis models, and promoting regeneration of damaged intestinal epithelium.

dTAG Targeting Ligand 1 (SUBSTITUTE SHEET 245) serves as a ligand for target proteins in PROTAC (Proteolysis Targeting Chimera) applications. It is used in the synthesis of PROTACs.

Alitame is a high-intensity sweetener and sugar substitute widely used in biochemical experiments and drug synthesis research.

Isoxaflutole (RP-201772) is a low toxic herbicide and has been marketed as a substitute for atrazine.

TCB-32 (Compound I-1) is an FGFR1 agonist with an EC50 of 0.88 μM. It enhances cell proliferation by activating FGFR1 and its downstream ERK1/2, exhibiting excellent thermal stability. TCB-32 can substitute bFGF in serum-free cell culture media and is applicable in research on tissue repair and wound healing-related conditions, such as psoriasis and eczema.

TCB-32 (Compound I-1) hydrochloride is an FGFR1 agonist with an EC50 of 0.88 μM. It stimulates cell proliferation by activating FGFR1 and its downstream ERK1/2 pathway, exhibiting excellent thermal stability. TCB-32 hydrochloride can substitute bFGF in serum-free cell culture media and is applicable in research related to tissue repair and wound healing diseases such as psoriasis and eczema.

PPACK Dihydrochloride is an efficient and selective irreversible thrombin inhibitor, which is often used in anticoagulant research, and can be used as a substitute anticoagulant for heparin lithium in blood gas and whole blood electrolyte analysis. PPACK is also used to regulate serine protease-related processes, which has application value in the study of thrombosis and fibrinolysis-related mechanisms.

Diplopterol is biosynthetic of squalene for use in acetobacter pasteurii in a cell-free system. It is a hopanoid and can be used as a substitute for sterols.

Ethyl aspartylphenylalaninate is an artificial non-saccharide sweetener used as a sugar substitute.