spermine

Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

N1-Azido-spermine trihydrochloride (Spermine[HHHN3]) is a click chemistry agent featuring an azide group.

Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical attack.

Naspm is a synthetic analogue of Joro spider toxin and is a antagonist iscalcium permeable AMPA (CP-AMPA) receptors.

Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and acts as an antagonist of calcium-permeable AMPA (CP-AMPA) receptors.

GL67 (N4-Spermine cholesteryl carbamate), a cationic lipid, facilitates the delivery of nucleic acid agents and vaccines, and is effective in gene transfection [1].

GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. It is utilized for the delivery of nucleic acid active molecules, vaccines, and for gene transfection.

Spermine Prodrug-1 is a redox-sensitive spermine prodrug. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblasts with IC50 values of 326.7. 198.5, and 244.1 μM, respectively. Spermine Prodrug-1 can be used in the treatment of Snyder Robinson syndrome.

Spermine (N3BBB), a click chemistry reagent with an azide group, facilitates diverse biochemical studies [1].

N4,N9-di-Boc-spermine is a spermine linker characterized by two Boc-protected amine groups and two additional amine groups. The Boc groups can be removed under mild acidic conditions to yield free amines. These amino groups can react with carboxylic acids, activated NHS esters, and carbonyl compounds (ketones, aldehydes). Spermidine, a polyamine, plays a role in regulating various cellular activities including cell growth and differentiation, DNA stability, and apoptosis.

N1,N12-Di-Boc-spermine is a spermine derivative that contains two Boc-protected amino groups. The Boc groups can be removed under mild acidic conditions to yield free amines. Spermidine, a related polyamine, plays a role in regulating diverse cellular processes, such as cell growth and differentiation, DNA stability, and apoptosis.

N-(4-Hydroxyphenylacetyl)spermine is a NMDA receptor antagonist.

Spermine (Standard) is the standard substance of Spermine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

Spermine tetrahydrochloride (Standard) is the standard substance of Spermine tetrahydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical attack.

N1-Acetylspermine trihydrochloride is a monoacetylated derivative of spermine which is an endogenous polyamine. N1-Acetylspermine trihydrochloride can be used in studies about the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16.

Thermospermine is a structural isomer of spermine that plays a role in inhibiting xylem differentiation and can enhance the translation of SAC51 and SACL1 in Arabidopsis thaliana. Thermospermine is also used in studies as a plant growth regulator and for controlling wood biomass production.

Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.

Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.

N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) is a diacetylated derivative of Spermine. The occurrence of cancer is associated with the up-regulation of N1,N12-Diacetylspermine dihydrochloride, making it a biomarker to detect cancer occurrence.

N1,N11-Diethylnorspermine (DENSPM), a spermine analog, serves as a potent anticancer agent by activating polyamine catabolism, which in turn triggers cytochrome c release from mitochondria and activates caspase 3. This process ultimately leads to the death of glioblastoma multiforme (GBM) cells by inducing spermidine/spermine N1-acetyltransferase (SSAT) activity along with the production of H2O2 [1] [2] [3].

Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT). A designed polyamines (PAs) analog which induces cell cycle arrest, inhibits proliferation and induces apoptosis in melanoma, breast, prostate, lung and colon cancer cells..

N1,N5,N10,N14-Tetra-trans-p-coumaroylspermine is a useful organic compound for research related to life sciences and the catalog number is T130733.

N1-Acetylspermine-d3 Trihydrochloride is the deuterated form of N1-Acetylspermine. As an endogenous metabolite found in urine, N1-Acetylspermine is useful for leukemia research.

N1,N12-Diacetylspermine-d6 (DiAcSpm-d6) is the deuterated form of N1,N12-Diacetylspermine.