nox 1

Irganox 1010 (Dovernox 10) is an agent of antioxidant.

Irganox 1010 (Standard) is the standard substance of Irganox 1010, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Irganox 1010 (Dovernox 10) is an agent of antioxidant.

APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.

GKT136901 hydrochloride is a NOX-1/4 inhibitor, a selective scavenger of peroxynitrite, which inhibits METH-induced ROS production.

Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.

1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 induced NOX activation and Smad signaling. 3. Decursin has anti-cancer activity , mediated suppression of the PKCα, MAPK and NF-κB pathways in MCF-7 cells. 4. Decursin exhibits cytotoxicity against various human cancer cells and to possess anti-amnesic activity in vivo through the inhibition of AChE activity.

GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM. It inhibits ROS production in isolated mouse cardiomyocytes and enhances their contractility. This compound is useful in research focused on ischemic cardiac injury [1].

GKT136901 (AK120765) is an inhibitor of NOX1 4.It acts as Selective and Direct Scavenger of Peroxynitrite