hypnotic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3563	Lvguidingan		Others
	Lvguidingan is an Anticonvulsant agent.		Others
T0992	Carbenoxolone disodium	Biogastrone,Duogastrone,Bioral	Gap Junction Protein
	Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ...		Gap Junction Protein
T0370	Pheniramine maleate	Daneral,Inhiston,Trimetose	5-HT Receptor , Histamine Receptor
	Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...		5-HT Receptor , Histamine Receptor
T30248	AZD 3043	AZD-3043,THRX 918661,AZD3043
	AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent.
T31724	Etoxybamide		Others
	Etoxybamide is a drug candidate for sedative (hypnotic).		Others
T0227	Bromisoval	2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,BRN 1773255,Bromovalerylurea,Bromaral	Others
	Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity.		Others
T14314	Apronal	Apronalide,Allylisopropylacetylurea	Others
	Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.		Others
T24451	Mepyramine	NSC-13136,NSC13136,NSC 13136
	Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
T19991	N-desmethylmirtazapine	N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838	Others
	N-desmethylmirtazapine (J1.061.658A) is a metabolite of mirtazapine. N-desmethylmirtazapine is also commonly used as an anxiolytic, hypnotic, antiemetic, and appetite stimulant.		Others
T10002	(E)-Crotylbarbital	Kalypnon	Others
	(E)-Crotylbarbital (Kalypnon), an isomer of Crotylbarbital, is a barbiturate derivative that has sedative, hypnotic, and anticonvulsant effects. (E)-Crotylbarbital can be used in studies to promote mental stability and s...		Others
TQ0023	Lorediplon		GABA Receptor
	Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.		GABA Receptor
T3282	Alimemazine hemitartrate	Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate	Others
	Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness.		Others
T0901	Chlorobutanol	Chlortran,Chloretone,YM-57158,Chlorbutol,Chloreton	Antibacterial , Antibiotic , Antifungal
	Chlorobutanol (Chlortran) is a chemical preservative, sedative hypnotic and weak local anaesthetic. It has Antibacterial and Antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lend...		Antibacterial , Antibiotic , Antifungal
T21428	Mianserin	Lantanon,Lumin,Norval,Lerivon,Depnon	Histamine Receptor
	Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family. Mianserin has antidepressant, antianxiety, antiemetic, hypotrophic, hypnotic and antihistam...		Histamine Receptor
T1232	Mepyramine maleate	Pyrilamine maleate	Histamine Receptor
	Mepyramine maleate (Pyrilamine maleate) is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. I...		Histamine Receptor
T24138	Hexapropymate	Lunamin,Esapropimato,L-2103,L2103,L 2103
	Hexapropymate is a hypnotic drug.
T13682	Epipregnanolone		Others
	Epipregnanolone is an endogenous neurosteroid with hypnotic and sedative effects.		Others
T29546	Acecarbromal	Paxerel,Absin,Darilonl,Adityl
	Acecarbromal is a central nervous system drug with potential hypnotic effects.
T27543	HIE-124
	HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.
T24201	JM-1232	JM 1232,MR 04A3,MR-04A3,MR04A3
	JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.
T34771	Taglutimide
	Taglutimide is a sedative-hypnotic derivative of glutarimide.
T26948	Capuride	NSC-27178,NSC27178,NSC-27690,NSC 27178,NSC27690
	Capuride is a sedative with hypnotic properties and possible anticonvulsant activity.
T27007	Chlormethiazole edisylate	Clomethiazole ethanedisulfonate,Clomethiazole edisylate,Heminevrin,Hemithiamine,Distraneurin
	Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.
T19318	Ethyl dirazepate		Others
	Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.		Others
T30945	Cinolazepam	Gerodorm,OX-373
	Cinolazepam is a benzodiazepine derivative drug.It has a powerful sedative effect, so it is mainly used as a hypnotic.
T28378	PF-0713	PF 0713,PF713
	PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.
T40205	Posovolone	Co 134444
	Posovolone (Co 134444), an orally active neuroactive steroid with sedative-hypnotic properties, exhibits anticonvulsant and anxiolytic-like activities, alongside ataxic effects.
T26061	Reposal	WT-161,Reposamal,Reposal novo,WT161,WT 161
	Reposal is a barbiturate derivative invented in the 1960s in Denmark. It has hypnotic, sedative, and anticonvulsant properties, and was used primarily for the therapy of insomnia.
T23604	Acebrochol
	Acebrochol is a neuroactive steroid. It may act as a sedative and hypnotic, by the mechanism of altering ligand-gated ion channels and cell surface receptors.
T68933	Gaboxadol hydrobromide
	Gaboxadol hydrobromide is a GABA agonist. It is an inhibitor of GABA uptake systems. Gaboxadol can also be a non-opioid analgesic and a novel type of hypnotic.
T69434	Methapyrilene fumarate
	Methapyrilene fumarate is a histamine H1 antagonist with sedative action used as a hypnotic and in allergies. It is a hepatocarcinogen in sufficiently high doses, inducing mutations through an indirect genotoxic mechanis...
T78111	NCS-382 sodium		GABA Receptor
	NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease research [1].		GABA Receptor
T68111	Nabitan
	Nabitan is an analogue of delta-9-tetrahydrocannabinol and was chosen on the basis of its sedative, hypnotic, and analgesic properties in animals.

Compounds

Lvguidingan

T3563

Synonym:

Target: Others

Carbenoxolone disodium

T0992

Synonym: Biogastrone,Duogastrone,Bioral

Target: Gap Junction Protein

Pheniramine maleate

T0370

Synonym: Daneral,Inhiston,Trimetose

Target: 5-HT Receptor, Histamine Receptor

AZD 3043

T30248

Synonym: AZD-3043,THRX 918661,AZD3043

Synonym: 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,BRN 1773255,Bromovalerylurea,Bromaral

Target: Others

Apronal

T14314

Synonym: Apronalide,Allylisopropylacetylurea

Target: Others

Mepyramine

T24451

Synonym: NSC-13136,NSC13136,NSC 13136

Target:

N-desmethylmirtazapine

T19991

Synonym: N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838

Target: GABA Receptor

Alimemazine hemitartrate

T3282

Synonym: Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate

Target: Others

Chlorobutanol

T0901

Synonym: Chlortran,Chloretone,YM-57158,Chlorbutol,Chloreton

Target: Antibacterial, Antibiotic, Antifungal

Mianserin

T21428

Synonym: Lantanon,Lumin,Norval,Lerivon,Depnon

Target: Histamine Receptor

Mepyramine maleate

T1232

Synonym: Pyrilamine maleate

Target: Histamine Receptor

Hexapropymate

T24138

Synonym: Lunamin,Esapropimato,L-2103,L2103,L 2103

Synonym: Paxerel,Absin,Darilonl,Adityl

Synonym: JM 1232,MR 04A3,MR-04A3,MR04A3

Synonym: NSC-27178,NSC27178,NSC-27690,NSC 27178,NSC27690

Target:

Chlormethiazole edisylate

T27007

Synonym: Clomethiazole ethanedisulfonate,Clomethiazole edisylate,Heminevrin,Hemithiamine,Distraneurin

Synonym: Gerodorm,OX-373

Target:

PF-0713

T28378

Synonym: PF 0713,PF713

Synonym: WT-161,Reposamal,Reposal novo,WT161,WT 161

Gaboxadol hydrobromide

T68933

Synonym:

Target:

Methapyrilene fumarate

Target: GABA Receptor

Cat No.	Product Name	Synonyms	Targets
T37709	2,2,2-Trichloroethanol		Potassium Channel , Endogenous Metabolite
	2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...		Potassium Channel , Endogenous Metabolite
T4S0675	Polygalasaponin V		Others
	Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk m...		Others
T7646	Alloepipregnanolone		Endogenous Metabolite
	Alloepipregnanolone is a pregnane with anesthetic, hypnotic, and sedative properties.		Endogenous Metabolite
T0330	Diphenhydramine hydrochloride	Diphenhydramine HCl,DPH	Histamine Receptor
	Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as...		Histamine Receptor
T8297	Gomisin N		Apoptosis
	Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits proliferation and induces apoptosis in cancer.		Apoptosis
TN1812	Jujuboside B1		5-HT Receptor
	Jujubosides have hypnotic effect on normal rats, may be influenced by circadian rhythm and the serotonergic system may involve in the hypnotic effect of jujubosides, jujubosides may be good source of lead compounds for n...		5-HT Receptor