hydrophobic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19033	Nile Red	Phenoxazone 9,Nile Blue A oxazone	Others
	Nile Red (Nile Blue A oxazone) is a strongly fluorescent stain used for the detection of intracellular lipid droplets in the presence of a hydrophobic environment.		Others
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T26087	Rilopirox
	Rilopirox is a synthetic fungicidal antimycotic with hydrophobic characteristics.
T19507	Perfluamine	FTPA,Tris(perfluoropropyl)amine,Perfluorotripropylamine	Others
	Perfluamine (FTPA) is a hydrophobic carrier fluid and can be used as a blood substitute.		Others
T19068	TMA-DPH		Others
	TMA-DPH is a hydrophobic fluorescent membrane probe (Ex: 355 nm; Em: 430 nm).		Others
T66152	NDSB-211		Others
	NDSB-211 is a surfactant with small hydrophobic ends and mildly solubilizes proteins for protein extraction and analysis.		Others
T4949	1,2-Didecanoyl-sn-glycero-3-phosphocholi	1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC	Others
	1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin.		Others
T72075	HyT36
	HyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3. HyT36 can treat cells expressing erht induced acutely.
T8032	4-Pentenoic acid		Others , Endogenous Metabolite
	4-Pentenoic acid, also known as allyl acetic acid or 4-pentenate, belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain. 4-Pentenoic acid is ...		Others , Endogenous Metabolite
T4072	Methyl-β-cyclodextrin	Methyl-beta-cyclodextrin,beta-Cyclodextrin methyl ethers	Others
	Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a macrocyclic compound used as a solubilizer for hydrophobic compounds in biological experiments. Methyl-β-cyclodextrin is also a lipid raft inhibitor with cholesterol-...		Others
T37482	Diclofenac methyl ester		Others
	Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not perme...		Others
T12492	Pivagabine	CXB-722	GABA Receptor
	Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor...		GABA Receptor
T9103	BVDV-IN-1		DNA/RNA Synthesis
	BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to...		DNA/RNA Synthesis
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T8782	MitoBloCK-11 (MB-11)		Others
	MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, con...		Others
T73499	NG-497	NG497	Lipase
	NG-497 is a selective, small molecule inhibitor of human adipose triglyceride lipase (ATGL) that targets the enzymatically active patatin-like structural domain of human ATGL.NG-497 binds ATGL in a hydrophobic lumen adja...		Lipase
T4889	2,6-Diaminoheptanedioic acid		Others , Endogenous Metabolite
	Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment...		Others , Endogenous Metabolite
T8098	γ-Hexalactone	γ-caprolactone	Others
	γ-Hexalactone (γ-caprolactone) belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-memb...		Others
T35841	5-Benzyloxygramine		Dopamine Receptor , 5-HT Receptor
	5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...		Dopamine Receptor , 5-HT Receptor
T19730	12-Crown-4	12 C 4,12-Crown-4 ether,12C4,12-C-4
	12-Crown-4 disrupts Aβ40 fibrils. 12-Crown-4 can enter into the hydrophobic core region and form competitive, hydrophobic interactions with key hydrophobic residues.