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  • DNA/RNA Synthesis
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Results for "

exonuclease

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    10
    TargetMol | Inhibitors_Agonists
  • Inhibitory Antibodies
    1
    TargetMol | Inhibitory_Antibodies
  • Recombinant Protein
    12
    TargetMol | Recombinant_Protein
CRT0044876
NSC 69877, 7-NO2-ICA, 7-Nitroindole-2-Carboxylic Acid
T64566960-45-8
CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
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Mirin
5-(4-Hydroxybenzylidene)-2-iminothiazolidin-4-one
T60273299953-00-7
Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor that inhibits MRN-dependent ATM activation without affecting ATM protein kinase activity. It also inhibits Mre11-associated exonuclease activity, thereby disrupting DNA double-strand break repair.Mirin induces cell cycle arrest in G1 phase.
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2-4 weeks
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(Z)-Mirin
Mirin
T31341198097-97-0
(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
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PFM39
T387091310744-67-2
PFM39 is a selective MRE11 nucleic acid exonuclease inhibitor and Mirin analog that prolongs mitosis.PFM39 inhibits HR and alleviates repair defects caused by EXO1 BLM depletion.
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7-10 days
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5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
T747021197033-19-4
5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].
  • Inquiry Price
8-10 weeks
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Carboxypeptidase B
T761029025-24-5
Carboxypeptidase B, a peptide exonuclease, specifically degrades peptide chains by progressively hydrolyzing from the C-terminal, releasing free amino acids. It acts exclusively on peptide bonds with basic amino acids (such as arginine and lysine) at the C-terminal residues [1] [2].
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Oleclumab
MEDI-9447, MEDI9447, MED I9447
T766951803176-05-7
Oleclumab (MEDI9447) is a human anti-CD73 monoclonal antibody with anticancer activity that inhibits the extracellular enzyme CD73 nucleic acid exonuclease activity, inhibits the adenosine pathway, and can be used for the study of metastatic desmoplasia-resistant prostate cancer.
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H3B-968
T789382912294-90-5
H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, targeting its helicase, ATPase, and exonuclease activities. While WRN is known for its synthetic lethal activity in cancer studies, H3B-968 specifically inhibits WRN's helicase function through competitive ATP antagonism [1].
  • Inquiry Price
8-10 weeks
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Dexamethasone metasulfobenzoate sodium
T885643936-02-5
Dexamethasone metasulfobenzoate sodium is an inhibitor of the SARS-CoV-2 exonuclease (ExoN), binding to the catalytic site of ExoN.
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10-14 weeks
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NSC 617145
NSC617145, NSC-617145
T9168203115-63-3
NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
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