estrone

Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derivative of Estrone that specifically binds to estrogen receptor α (ERα). With a linker, it complexes with the cIAP1 ligand Bestatin, forming SNIPER[1].

Estrone 3-methyl ether is an active molecule that can be used in life science related research. The CAS number of Estrone 3-methyl ether is 1624-62-0.

Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigated as a ligand for targeting organic anion transporting polypeptides f

4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.

Oleoylestrone (MP-101) is present in plasma and adipose tissue, has potential antioxidant effects, induces loss of body fat in rats, and can be used for weight loss.

Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS), showing IC50 values of 18 nM as a placental microsomal inhibitor (P.M.) and 0.83 nM in MCF-7 cells. Estrone O-sulfamate can be used to study cancer.

Estrone-3-Glucuronide sodium hydrate is the major metabolite of estrone, serving as a biological marker for sex determination in the Chinese giant salamander.

4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) is the methylation of 4-OHE1, which is catalyzed by COMT.

Estrone-D2 (Standard) is a reference standard of Estrone-D2 intended for quantitative analysis, quality control, and related biochemical research applications. Estrone-d2 is a deuterated compound of Estrone. Estrone has a CAS number of 53-16-7. Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Estrone-D4 (Standard) is a reference standard of Estrone-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Estrone-d4 is a deuterated compound of Estrone. Estrone has a CAS number of 53-16-7. Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Estrone-D4 3-Sulfate Sodium Salt (Standard) is a reference standard of Estrone-D4 3-Sulfate Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications. Estrone-d4 3-Sulfate Sodium Salt is a deuterated compound of Estrone 3-Sulfate Sodium Salt. Estrone 3-Sulfate Sodium Salt has a CAS number of 438-67-5.

Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.

Estradiol 3-sulfamate (BLE 00084) is an orally active and highly potent steroidal estrone sulfatase (ES) inhibitor.Estradiol 3-sulfamate has a K(i) value of 73 nM for ES in human placental microsomes and can be used in the study of breast cancer.

Estropipate (Piperazine estrone sulfate) is a natural estrogenic substance composed of estrone sulfate and piperazine.

Estrone acetate (Hogival) is an estrogen derivative and an activator of estrogen receptors (ER). This compound can enhance breast development, stimulate the secretion of pituitary prolactin, and induce both the proliferation and activation of lactotrophs, evidenced by the reduction in prolactin storage granule size and the increase in the volume density of the rough endoplasmic reticulum and Golgi apparatus. Estrone acetate holds potential for endocrinological research and for investigating the mechanisms by which estrogen influences pituitary function, prolactin regulation, and breast tumor models.

Estrone 3-glucuronide is a urinary metabolite of estradiol and can be used as a urinary marker to predict the fertile window.

Estrone 3-methyl ether (Standard) is a reference standard for research and analysis in studies involving Estrone 3-methyl ether. Estrone 3-methyl ether is an active molecule that can be used in life science related research. The CAS number of Estrone 3-methyl ether is 1624-62-0.

Estrone-3-Glucuronide sodium is a coupled metabolite of estrone, which is formed in the liver by UDP-glucuronyltransferase through glucuronide coupling.

Estrone sulfate potassium is an estrogen ester and conjugate, a natural endogenous steroid.

Estrone-D4 is a deuterated compound of Estrone. Estrone (T1009) has a CAS number of 53-16-7. Estrone (T1009) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Estrone-D4 3-Sulfate Sodium Salt is a deuterated compound of Estrone 3-Sulfate Sodium Salt. Estrone 3-Sulfate Sodium Salt (T36857) has a CAS number of 438-67-5.

Estrone-D2 is a deuterated compound of Estrone. Estrone (T1009) has a CAS number of 53-16-7. Estrone (T1009) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Estrone (Standard) is the standard substance of Estrone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.