epm

Diclazuril (R-64433) is a coccidiostat.

Epmedin C (Baohuoside-VI) was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential activity against osteoporosis by stimulating osteoblasts.

DEPMPO (5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide) is a spin trapping agent in biological systems and can be used to detect free radicals in lipid phases.

DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance. It is noted for the stability of adducts formed. DEPMPO can be used in vitro or in vivo, as it crosses lipid bilayer membranes and is a good trapping agent in biological systems. DEPMPO-biotin is a biotinylated form of DEPMPO which retains the outstanding persistency of its adducts. The biotin moiety offers an effective means for monitoring biodistribution in cells, tissues, and organs when used with an avidin-conjugated reporter. Importantly, DEPMPO-biotin binds free radicals, such as S-nitroso groups, on proteins, producing adducts that can be analyzed via the biotin tag. This direct labeling of S-nitrosothiols (SNO) thus serves as an effective alternative to the more cumbersome biotin-switch method for monitoring SNO formation.

Epmedin C (Standard) is a reference standard for research and analysis in studies involving Epmedin C. Epmedin C (Baohuoside-VI) was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential activity against osteoporosis by stimulating osteoblasts.

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesize various compounds.

MTC420 is a anti-tuberculosis agent with acceptable anti-tuberculosis activity (Mtb IC50 =525 nM, Mtb Wayne IC50 = 76 nM and MDR Mtb patient isolates IC50 = 140 nM).

1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.

[2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][[5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]diphenylphosphine-κP](methanesulfonato-κO)palladium is a useful organic compound for research related to life sciences. The catalog number is T66571 and the CAS number is 1445085-97-1.

Hyaluronan synthase (PmHAS), a membrane protein, catalyzes the biosynthesis of hyaluronic acid (HA) by utilizing only Mg+2 along with two sugar-UDP substrates, GlcUA-UDP and GlcNAc-UDP, to polymerize HA chains [1] [2].

Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1].

SMAP 29, a bactericidal antimicrobial peptide and a cleavage product from the C-terminus of an ovine cathelicidin prepropeptide, is effective against P. aeruginosa strain PAO1 in both low- and high-salt conditions, as demonstrated in an energy-dependent luminescence assay with half-maximal effective concentrations (EC50s) of 0.05 and 0.06 µM, respectively. Additionally, it induces hemolysis in ovine red blood cells in a concentration-dependent manner.

Heparin Methacrylate (HepMA) is a heparin derivative, modified with methacrylate, making it suitable as a material for tissue engineering scaffolds and as a bioink for 3D printing. Under the influence of the photoinitiator LAP , HepMA self-assembles into fibrous hydrogels that target bioactive adhesion sites, providing inherent support to tissue cells and promoting biodegradation. Its applications include cell culture, bioprinting, and tissue engineering.

Me-PMeOx(50)-N3 (MW 4.3kDa) is a click chemistry reagent. Click chemistry offers significant potential for linking nucleic acids, lipids, proteins, and other molecules due to its beneficial properties such as high yield, high specificity, and simplicity, making it valuable in numerous research fields. This compound contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

Me-PMeOx(100)-N3 (MW 8.5kDa) is a reagent utilized in click chemistry, which offers significant potential for joining nucleic acids, lipids, proteins, and other molecules. Valued for its high yield, specificity, and simplicity, it sees widespread application in various research fields. Equipped with an Azide group, it can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Alkyne group. Additionally, it participates in strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.