dbc

DBC, a ubiquitous environmental pollutant, induces significant DNA strand break levels and micronuclei in HepG2 cells.

DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into an azide-labelled biomolecule via a copper-free catalytic alkyl azide reaction (SPAAC). azide-labelled biomolecules via a copper-free catalytic alkyl azide reaction (SPAAC).

DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.

BDP FL DBCO, a cleavable linker crucial in ADC synthesis, connects cytotoxic drugs to antibodies for targeted delivery to cells or proteins. Its cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

DBCO-acid is a cleavable ADC linker utilized in the synthesis of ADC linker DBCO-NHS ester and drug-linker conjugates DBCO-PEG-MMAE[1].

DBCO-amine is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-C6-acid is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) and carmaphycin analogues[1].

DBCO-Maleimide (DBCO-MAL) is a non-cleavable ADC linker for the synthesis of ADC compounds.

DBCO-Amide-PEG5-acid is a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].

DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

DBCO-NHS ester 2 is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) and is a Dibenzylcyclooctyne (DBCO) derivative designed for copper-free click chemistry [1].

DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].

DBCO-PEG4-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-PEG4-Maleimide is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

DBCO-PEG5-NHS ester is a PROTAC linker belonging to the PEG and Alkyl ether classes for the synthesis of a range of PROTAC molecules.

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

DBCO-Sulfo-Link-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.