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(9)
By Target- Chk
- CDK(2)
- Apoptosis(1)
- Aurora Kinase(1)
- FGFR(1)
- FLT(1)
- JAK(1)
- Src(1)
- Tyrosine Kinases(1)
- VEGFR(1)
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Results for "
chk 2
" in TargetMol Product Catalog- Inhibitors & Agonists9
- Natural Products1
- Recombinant Protein2
- Antibody Products1
Baricitinib
LY3009104, INCB028050
T24851187594-09-7
Baricitinib (INCB028050) is a JAK1 and JAK2 inhibitor (IC50=5.9 5.7 nM) with selective and oral activity. Baricitinib has potential anti-inflammatory, immunomodulatory and anti-tumor activity.
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Prexasertib
LY2606368
T43101234015-52-1
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
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cct241533
T107181262849-73-9In house
CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
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sch900776
MK-8776, MK 8776
T2517891494-63-6
SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.
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azd-7762
AZD7762
T6093860352-01-8
AZD-7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
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4-Demethyldeoxypodophyllotoxin
T833213590-93-0
4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.
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cct241533 hydrochloride
T10718L1431697-96-9
CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
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PF 477736
PF-477736, PF477736, PF 00477736
T6028952021-60-2
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
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CHK1-IN-2
T10790912367-45-4
CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).
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