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Results for "

cd 246

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    6
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    2
    TargetMol | Recombinant_Protein
Crizotinib
PF-02341066
T1661877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
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Entrectinib
RXDX-101, NMS-E628
T36781108743-60-7
Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1 3 5 12 7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity.
  • $35
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R-268712
T16708879487-87-3
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
  • $39
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CEP-28122
T26121022958-60-6
CEP-28122 is a highly potent and selective, orally active ALK inhibitor.
  • $50
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hg-14-10-04
T40151356962-34-9
HG-14-10-04 is a potent and specific ALK (anaplastic lymphoma kinase) inhibitor.
  • $44
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Crizotinib hydrochloride
PF-02341066 hydrochloride
T83991415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met, with IC50 values of 20 nM and 8 nM, respectively.
  • $31
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