association — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8773	MID-1		Others , IGF-1R
	MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skelet...		Others , IGF-1R
T6343	Geldanamycin	NSC 122750	HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
	Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
T8955	PCNA-I1		Others
	PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.		Others
T22195	CBFβ Inhibitor	5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine	DNA/RNA Synthesis
	CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.		DNA/RNA Synthesis
T8774	MS7972		Epigenetic Reader Domain
	MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM		Epigenetic Reader Domain
TN1048	Cnidilin	Knidilin
	Cnidilin (Knidilin) is found in association with Angelica dahurica roots, has high BBB permeability and has pharmacokinetic potential in the treatment of CNS disorders.
T4767	Formamide	Carbamaldehyde,Methanamide,NSC 748,Formimidic acid	Others , Endogenous Metabolite
	Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent deve...		Others , Endogenous Metabolite
TP1313L	Cecropin B acetate	Cecropin B acetate(80451-05-4 Free base)	P450 , Retinoid Receptor , Parasite
	Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences. Cecropin B acetate exhibits strong antimicrobial a...		P450 , Retinoid Receptor , Parasite
TP1777L	P2Ca acetate(142606-55-1 free base)		Others
	p2Ca acetate is a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).		Others
T26357	Pitstop 2		Apoptosis
	Pitstop2 is a selective inhibitor of amphiphysin association of clathrin terminal domain with an IC50 value of 12 μM. Pitstop2 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle rec...		Apoptosis
T11728	JR-AB2-011		mTOR
	JR-AB2-011 is a selective mTORC2 inhibitor with an IC 50 value of 0.36 μM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association ( K i : 0.19 μM) and is cytotoxic in glioblastoma [1].		mTOR
T9033	BTYNB	MDK6620,BTYNB IMP1 Inhibitor	Others , c-Myc , NF-κB
	BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ...		Others , c-Myc , NF-κB
T73593	PDS-0330		Others
	PDS-0330 is a claudin-1 small molecule inhibitor inhibitor.PDS-0330 inhibits claudin-1-dependent CRC progression and binds directly and specifically to claudin-1 with micromolar affinity.PDS-0330 exhibits well characteri...		Others
T37807	JTV 519 fumarate
	Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]r...
T9533	BC-LI-0186	4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...		Others
TP2309	NEUROTENSIN TFA (39379-15-2 free base)	Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA	Others
	Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a...		Others
T23745	APA-APA-MPO	APA APA MPO,APAAPAMPO
	APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T23746	APA-H-MPO	APAHMPO
	APA-H-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.
T26382	2-Mc-1,4-NHQ	NSC 111552,NSC-111552,NSC111552
	2-Mc-1,4-NHQ, an inhibitor of the Cdc42-PBD interaction, blocks the association of Cdc42 with the PBD.
T16423	P32 Inhibitor M36	M36	Others
	p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.		Others