alox-5

5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1(PAK1) and NF-Κb. 5-Aminosalicylic Acid has anti-cancer and anti-inflammatory activities. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).

Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cognition, and mentally stimulating effect.

Diethylcarbamazine citrate (Caritrol) is an anthelmintic used primarily as the citrate in the treatment of filariasis, particular infestations with Wucheria bancrofti or Loa loa. It is an inhibitor of arachidonic acid metabolism in filarial microfilaria.

4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.

ALOX5 stabilizer-1 is an inhibitor of arachidonic acid 5-lipoxygenase (ALOX5) with a Kd value of 7.26 μM. It reduces protein levels of β-catenin and subsequently inhibits the STAT3 signaling pathway. ALOX5 stabilizer-1 induces apoptosis in lung cancer cells and hampers their migration and proliferation, making it useful for research on non-small cell lung cancer (NSCLC).