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Results for "

a cardiac muscle 1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    9
    TargetMol | Inhibitors_Agonists
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    2
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TargetMolTargetMolCompare
ACTA1 Protein, Human, Recombinant (Baculovirus, His)
Alpha-cardiac actin, alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, ACTC1, ACTC
TMPH-03785
Expression system: Baculovirus Insect Cells
Length: 3-377, Partial
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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TNNC1 Protein, Human, Recombinant (His)
Troponin I, TNNI3, TNNC1, CMH7
TMPJ-00044
Expression system: E. coli
Length: 1-161, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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CT-1 Protein, Human, Recombinant (His)
CTF1, CT-1, Cardiotrophin-1
TMPJ-00086
Expression system: E. coli
Length: 1-201, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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CD117 Protein, Human, Recombinant (hFc)
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, Tyrosine-protein kinase Kit, SCFR, Proto-oncogene c-Kit, Piebald trait protein, PBT, p145 c-kit, Mast stem cell growth factor receptor Kit, KIT, CD117
TMPJ-00402
C-Kit SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1 PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing stimuli, and it is required for subsequent dendritic cell induction of Th2 and Th17 responses. SCF R protects vascular smooth muscle cells from apoptosis and assists in the recovery of cardiac function following myocardial infarction.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer
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Desmin Protein, Human, Recombinant (His)
Desmin, DES
TMPJ-00882
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer
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PRKG1 Protein, Human, Recombinant (His)
PRKGR1B, PRKGR1A, PRKG1B, PRKG1, cGMP-Dependent Protein Kinase I, cGMP-Dependent Protein Kinase 1, cGKI, cGK1, cGK 1
TMPJ-01112
cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO) cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-signaling pathway, and other processes involved in several aspects of the CNS like axon guidance, hippocampal and cerebellar learning, circadian rhythm, and nociception.
  • Inquiry Price
7-10 days
Size
QTY
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RheB Protein, Human, Recombinant (GST)
RHEB2, RHEB, Ras Homolog Enriched in Brain, GTP-Binding Protein Rheb
TMPJ-01126
Expression system: E. coli
Length: 1-184, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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LMCD1 Protein, Human, Recombinant (His)
LMCD1, LIM and cysteine-rich domains protein 1, Dyxin
TMPJ-01364
Expression system: E. coli
Length: 1-365, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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ECE1 Protein, Human, Recombinant (His)
RP3-329E20.1, endothelin converting enzyme 1, ECE
TMPY-01929
Endothelin-converting enzyme 1, also known as ECE-1, is a single-pass type II membrane protein which belongs to thepeptidase M13 family. ECE-1 converts big endothelin-1 to endothelin-1. ECE-1 is a membrane metalloprotease that generates endothelin from its direct precursor big endothelin. Four isoforms of ECE-1 are produced from a single gene through the use of alternate promoters. These isoforms share the same extracellular catalytic domain and contain unique cytosolic tails, which results in their specific subcellular targeting.All isoforms of ECE-1 are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C of ECE-1 are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C of ECE-1 in liver, testis and small intestine; isoform B, C and D of ECE-1 in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. Defects in ECE1 are a cause of Hirschsprung disease, cardiac defects and autonomic dysfunction. It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer
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PDE1C Protein, Human, Recombinant (His & GST)
phosphodiesterase 1C, calmodulin-dependent 70kDa, hCam-3, Hcam3, cam-PDE1C
TMPY-02977
Expression system: Baculovirus Insect Cells
Length: 1-634, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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Calsequestrin 1 Protein, Human, Recombinant
VMCQA, PDIB1, CASQ, calsequestrin 1 (fast-twitch, skeletal muscle)
TMPY-03438
Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. Two forms of calsequestrin have been identified: Calsequestrin-2 and Calsequestrin-1. Calsequestrin-1 is found in fast skeletal muscle. The release of calsequestrin-bound calcium (through a calcium release channel) triggers muscle contraction. The active protein is not highly structured, more than 5% of it adopting a random coil conformation. When calcium binds there is a structural change whereby the alpha-helical content of the protein increases from 3 to 11%. Both forms of calsequestrin are phosphorylated by casein kinase 2, but the cardiac form is phosphorylated more rapidly and to a higher degree. Calsequestrin-1 is also secreted in the gut where it deprives bacteria of calcium ions.
  • Inquiry Price
7-10 days
Size
QTY
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AKT2 Protein, Human, Recombinant (His & GST)
v-akt murine thymoma viral oncogene homolog 2, RAC-β, RAC-BETA, PRKBB, PKBβ, PKBBETA, PKBB, HIHGHH
TMPY-04387
Expression system: Baculovirus Insect Cells
Length: 1-481, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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AKT1 Protein, Human, Recombinant (His)
v-akt murine thymoma viral oncogene homolog 1, RAC-α, RAC-ALPHA, RAC, PRKBA, PKB-α, PKB-ALPHA, PKB, CWS6, AKT
TMPY-04552
Expression system: Baculovirus Insect Cells
Length: 1-480, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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SGK3 Protein, Human, Recombinant (His & GST)
SGKL, SGK2, serum glucocorticoid regulated kinase family, member 3, CISK
TMPY-04561
Expression system: Baculovirus Insect Cells
Length: 1-496, Full Length
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY