Tachykinin receptor

Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family.

R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.

gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate possesses higher affinity than NKA for central NK-2 receptors; it shows lower affinity for NK-1 receptors, however, it potently stimulates salivary secretion, which is mediated by NK-1 receptor activation.

Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).

Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).

Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.

Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.

Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.

Potent and selective tachykinin NK2 receptor antagonist

MEN 10207 is an antagonist of tachykinin.

MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.

R 396 (Acleu-asp-gln-trp-phe-glynh2) is a linear hexapeptide and is also an NK-2 tachykinin receptor antagonist.

Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects

Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .

Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .

Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, functions via the NK-2 receptor and acts as a key mediator in human airway and gastrointestinal tissues [1].

Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist [1].

Hemokinin 1, human TFA acts as a selective full agonist at the tachykinin neurokinin 1 (NK1) receptor, while also being a full agonist at NK2 and NK3 receptors. It is capable of inducing opioid-independent analgesia [1] [2].

Men 10376 TFA is a selective antagonist of the tachykinin NK-2 receptor, exhibiting a K_i value of 4.4 μM for the NK-2 receptor in rat small intestine [1].

[Pro9]-Substance P is a highly effective, reversible, and selective NK-1 tachykinin receptor agonist with an EC50 value of 0.93 nM [1].

Phyllomedusin, a tachykinin decapeptide, acts as an NK1 receptor agonist. It exhibits vasodilatory effects and induces pyloric contractions [1] [2] [3].

Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand.

Eledoisin Related Peptide 2TFA (Eledoisin Related Peptide 2TFA (2990-43-4(free base))) is a tachykinin receptor ligand.

Senktide is an agonist of tachykinin NK3 receptor.