papain — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19503	Papain		Others , Cysteine Protease
	Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.		Others , Cysteine Protease
T21521L	Papain Inhibitor acetate	GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate （70195-20-9 free base)	Others
	Papain Inhibitor acetate (Gly-Gly-Tyr-Arg) is an affinity Ligand for Papain.		Others
T6037	E-64	Proteinase inhibitor E 64,E 64,E64	Cysteine Protease , Antibacterial , Autophagy
	E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.		Cysteine Protease , Antibacterial , Autophagy
T65868	Z-Lys-OH		Cysteine Protease
	Z-Lys-OH is a competitive inhibitor of papain, a lysine derivative.		Cysteine Protease
T12502	PLpro inhibitor		SARS-CoV
	PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)		SARS-CoV
T9606	TC-067533		SARS-CoV
	TC-067533 is a Papain-like protease inhibitor with an IC50 of 8.7 μM.		SARS-CoV
T3S0136	4'-O-Methylbavachalcone	O-Methylbroussochalcone B	SARS-CoV
	4'-O-Methylbavachalcone (O-Methylbroussochalcone B) is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity (IC50: 10.1 μM).		SARS-CoV
T78704	PLpro/RBD-IN-1		SARS-CoV
	PLpro/RBD-IN-1 (Compound 5) serves as a dual inhibitor targeting both the SARS-CoV-2 papain-like protease (PLpro) and the receptor-binding domain (RBD) of the spike protein, exhibiting half-maximal inhibitory concentrati...		SARS-CoV
T18911	Acriflavine	Acriflavinium chloride 3,6-Acridinediamine mix	SARS-CoV , Antibacterial
	Acriflavine (Acriflavinium chloride 3,6-Acridinediamine mix) is a papain-like protease (PL(pro)) inhibitor, a fluorescent dye for labeling high molecular weight RNAs, has antimicrobial and anticancer activity, inhibits S...		SARS-CoV , Antibacterial
T36352	Suc-Leu-Tyr-AMC
	Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em...
T2O2733	L-Cystine	Cystine Acid,cystine	Antioxidant , Ferroptosis , Endogenous Metabolite
	L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cysteine amino acid thiol side chains. It functions as an antiox...		Antioxidant , Ferroptosis , Endogenous Metabolite
T61500	PLP_Snyder530
	PLP_Snyder530 is a potent papain-like protease (PL pro ) inhibitor. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-C...
T63292	SARS-CoV-2-IN-24
	SARS-CoV-2-IN-24 is a potent inhibitor of papain-like proteases (PLpro) that induces conformational changes in SARS-COV-2 papain-like proteases, inhibits SARS-COV-2 replication, and can be used to study SARS-CoV-2.
T26202	SP-Chymostatin B	alpha-Mapi
	SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. I...
T63443	XR8-89
	XR8-89, a potent inhibitor of papain-like protease (PLpro), exhibits an IC50 value of 0.1 μM and effectively hinders SARS-CoV-2 replication by inducing conformational changes in the SARS-COV-2 papain-like protease. This ...
TP2056	Acetyl-Calpastatin(184-210)(human)	Acetyl-Calpastatin (184-210) (human)
	Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
T60841	SARS-CoV-2-IN-23
	SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].
T80739	Z-FG-NHO-BzOME
	Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S, and papain [1].
T69297	Leupeptin HCl
	Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin...
T81202	SARS-CoV-2-IN-69		SARS-CoV
	SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-like protease (PL^pro) [1].		SARS-CoV